Wavefront shaping using a deformable mirror for focusing inside optical tissue phantoms

Ricardo Gomes; João M P Coelho; Ana Gabriel; Pedro Vieira; Catarina Oliveira Silva; Catarina Reis

doi:10.1117/12.2063539

Wavefront shaping using a deformable mirror for focusing inside optical tissue phantoms

Ricardo Gomes, João M P Coelho, Ana Gabriel, Pedro Vieira, Catarina Oliveira Silva, Catarina Reis

DF – Departamento de Física

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

3 Citations (Scopus)

Abstract

Although light has long being used in medicine, scattering always hindered its use. This study intends to evolve into three different frontlines: development of methodologies to concentrate light inside biological tissues, development of an optical tissue phantom and development of multifunctional gold nanoparticles with therapeutic potential for targeting anticancer drug delivery. The impact of the scattering agent (milk) concentration in the measured wavefront and spot radius is analyzed. Wavefront correction proves to be efficient in overcoming the scattering effect in the different phantoms. Future studies for developing a photodynamic approach under near-infrared wavelength are now in progress and will be further presented.

Original language	English
Title of host publication	Second International Conference on Applications of Optics and Photonics
Publisher	Spie -- the Int Soc for Optical Engineering
Volume	9286
ISBN (Electronic)	9781628413618
DOIs	https://doi.org/10.1117/12.2063539
Publication status	Published - 2014
Event	2nd International Conference on Applications of Optics and Photonics - Aveiro, Portugal Duration: 26 May 2014 → 30 May 2014

Conference

Conference	2nd International Conference on Applications of Optics and Photonics
Country	Portugal
City	Aveiro
Period	26/05/14 → 30/05/14

Keywords

Multifunctional gold nanoparticles
Optical tissue phantom
Scattering
Wavefront shaping

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10.1117/12.2063539

Cite this

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title = "Wavefront shaping using a deformable mirror for focusing inside optical tissue phantoms",

abstract = "Although light has long being used in medicine, scattering always hindered its use. This study intends to evolve into three different frontlines: development of methodologies to concentrate light inside biological tissues, development of an optical tissue phantom and development of multifunctional gold nanoparticles with therapeutic potential for targeting anticancer drug delivery. The impact of the scattering agent (milk) concentration in the measured wavefront and spot radius is analyzed. Wavefront correction proves to be efficient in overcoming the scattering effect in the different phantoms. Future studies for developing a photodynamic approach under near-infrared wavelength are now in progress and will be further presented.",

keywords = "Multifunctional gold nanoparticles, Optical tissue phantom, Scattering, Wavefront shaping",

author = "Ricardo Gomes and Coelho, {Jo{\~a}o M P} and Ana Gabriel and Pedro Vieira and {Oliveira Silva}, Catarina and Catarina Reis",

year = "2014",

doi = "10.1117/12.2063539",

language = "English",

volume = "9286",

booktitle = "Second International Conference on Applications of Optics and Photonics",

publisher = "Spie -- the Int Soc for Optical Engineering",

note = "2nd International Conference on Applications of Optics and Photonics ; Conference date: 26-05-2014 Through 30-05-2014",

}

Gomes, R, Coelho, JMP, Gabriel, A, Vieira, P, Oliveira Silva, C & Reis, C 2014, Wavefront shaping using a deformable mirror for focusing inside optical tissue phantoms. in Second International Conference on Applications of Optics and Photonics. vol. 9286, 92863Z, Spie -- the Int Soc for Optical Engineering, 2nd International Conference on Applications of Optics and Photonics, Aveiro, Portugal, 26/05/14. https://doi.org/10.1117/12.2063539

Wavefront shaping using a deformable mirror for focusing inside optical tissue phantoms. / Gomes, Ricardo; Coelho, João M P; Gabriel, Ana; Vieira, Pedro; Oliveira Silva, Catarina; Reis, Catarina.

Second International Conference on Applications of Optics and Photonics. Vol. 9286 Spie -- the Int Soc for Optical Engineering, 2014. 92863Z.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Wavefront shaping using a deformable mirror for focusing inside optical tissue phantoms

AU - Gomes, Ricardo

AU - Coelho, João M P

AU - Gabriel, Ana

AU - Vieira, Pedro

AU - Oliveira Silva, Catarina

AU - Reis, Catarina

PY - 2014

Y1 - 2014

N2 - Although light has long being used in medicine, scattering always hindered its use. This study intends to evolve into three different frontlines: development of methodologies to concentrate light inside biological tissues, development of an optical tissue phantom and development of multifunctional gold nanoparticles with therapeutic potential for targeting anticancer drug delivery. The impact of the scattering agent (milk) concentration in the measured wavefront and spot radius is analyzed. Wavefront correction proves to be efficient in overcoming the scattering effect in the different phantoms. Future studies for developing a photodynamic approach under near-infrared wavelength are now in progress and will be further presented.

AB - Although light has long being used in medicine, scattering always hindered its use. This study intends to evolve into three different frontlines: development of methodologies to concentrate light inside biological tissues, development of an optical tissue phantom and development of multifunctional gold nanoparticles with therapeutic potential for targeting anticancer drug delivery. The impact of the scattering agent (milk) concentration in the measured wavefront and spot radius is analyzed. Wavefront correction proves to be efficient in overcoming the scattering effect in the different phantoms. Future studies for developing a photodynamic approach under near-infrared wavelength are now in progress and will be further presented.

KW - Multifunctional gold nanoparticles

KW - Optical tissue phantom

KW - Scattering

KW - Wavefront shaping

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U2 - 10.1117/12.2063539

DO - 10.1117/12.2063539

M3 - Conference contribution

AN - SCOPUS:84922738379

VL - 9286

BT - Second International Conference on Applications of Optics and Photonics

PB - Spie -- the Int Soc for Optical Engineering

T2 - 2nd International Conference on Applications of Optics and Photonics

Y2 - 26 May 2014 through 30 May 2014

ER -

Wavefront shaping using a deformable mirror for focusing inside optical tissue phantoms

Abstract

Conference

Keywords

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