Hipersensibilidade à varfarina: que abordagem?

Translated title of the contribution: Warfarin hipersensitivity: how to deal with it?

Ana Furtado Lima, José Reis, Fátima Serrano, Augusta Borges

Research output: Contribution to journalArticlepeer-review

33 Downloads (Pure)

Abstract

The authors report a clinical case of warfarin hypersensitivity noticed when a patient, with thromboembolic risk, was submitted to warfarin. She was found to be heterozigotic to -1639G>A (gene VKORC1) and homozygotic to 1075A>C (genotype CYP2C9*3/*3). In this article the warfarin pharmacodinamics and its role over Vitamin K is revisited. It includes some suggested indications for investigating genetic polymorphisms, in order to avoid complications associated with warfarin.
Translated title of the contributionWarfarin hipersensitivity: how to deal with it?
Original languagePortuguese
Pages (from-to)727-30
Number of pages4
JournalActa medica portuguesa
Volume23
Issue number4
Publication statusPublished - Jul 2010

Keywords

  • VKORC1
  • POPULATION
  • RESISTANCE

Fingerprint

Dive into the research topics of 'Warfarin hipersensitivity: how to deal with it?'. Together they form a unique fingerprint.

Cite this