TY - JOUR
T1 - Vasa Vasorum Changes Following Stent Placement in Experimental Arterial Stenoses
AU - Pisco, João Martins
AU - Correia, Miguel
AU - Esperança-Pina, José A.
AU - de Sousa, Luis Aires
PY - 1993
Y1 - 1993
N2 - Experimental stenoses were created in canine aortae to compare the effects of stent placement and balloon angioplasty on the vasa vasorum. A balloon-expandable Palmaz stent was placed in the proximal stenosis, and angioplasty was performed in the distal stenosis in each of eight dogs. Two dogs were killed at 4, 8,12, and 18 months, respectively. Specimens were studied by means of microangiography, histology, scanning electronic microscopy, and Spalteholz technique. At up to 12 months, there was proliferation of the vasa vasorum and a rich plexus formed in each of the animals at each treated site. More vasa vasorum were seen after stent placement than after angioplasty. The new vessels were mainly venules located in the media. At 18 months, there was regression of the venules and the vasa vasorum distribution returned to baseline. The authors conclude that the effects of stents on the vasa vasorum are temporary.
AB - Experimental stenoses were created in canine aortae to compare the effects of stent placement and balloon angioplasty on the vasa vasorum. A balloon-expandable Palmaz stent was placed in the proximal stenosis, and angioplasty was performed in the distal stenosis in each of eight dogs. Two dogs were killed at 4, 8,12, and 18 months, respectively. Specimens were studied by means of microangiography, histology, scanning electronic microscopy, and Spalteholz technique. At up to 12 months, there was proliferation of the vasa vasorum and a rich plexus formed in each of the animals at each treated site. More vasa vasorum were seen after stent placement than after angioplasty. The new vessels were mainly venules located in the media. At 18 months, there was regression of the venules and the vasa vasorum distribution returned to baseline. The authors conclude that the effects of stents on the vasa vasorum are temporary.
KW - Arteries, grafts and prostheses, 9.1268, 9.1282
KW - Blood vessels, foreign bodies, 9.1268, 9.1282
KW - Stents, 9.1268
UR - http://www.scopus.com/inward/record.url?scp=0027569827&partnerID=8YFLogxK
U2 - 10.1016/S1051-0443(93)71851-5
DO - 10.1016/S1051-0443(93)71851-5
M3 - Article
C2 - 8481575
AN - SCOPUS:0027569827
SN - 1051-0443
VL - 4
SP - 269
EP - 273
JO - Journal of Vascular and Interventional Radiology (JVIR)
JF - Journal of Vascular and Interventional Radiology (JVIR)
IS - 2
ER -