TY - JOUR
T1 - Using a bacterial fucose-rich polysaccharide as encapsulation material of bioactive compounds
AU - Lourenço, Sofia C.
AU - Torres, Cristiana A.V.
AU - Nunes, Daniela
AU - Duarte, Paulo
AU - Freitas, Filomena
AU - Reis, Maria A.M.
AU - Fortunato, Elvira
AU - Moldão-Martins, Margarida
AU - da Costa, Luísa Beirão
AU - Alves, Vítor D.
N1 - sem pdf conforme despacho.
Fundacao para a Ciencia e Tecnologia, Portugal, for projects UID/Multi/04378/2013, PTDC/AGR-ALI/114706/2009, PEst-OE/AGR/UI0245/2013 and UID/CTM/50025/2013, and fellowships SFRH/BPD/87774/2012 and SFRH/BPD/72280/2010.
PY - 2017/11/1
Y1 - 2017/11/1
N2 - The potential of a bacterial exopolysaccharide named FucoPol, produced by the bacterium Enterobacter A47, as encapsulation matrix was explored. Spherical capsules with a smooth surface were produced by spray drying. The obtained microcapsules had average diameters ranging from 0.5 to 26.7 μm and presented thin walls (thickness from 222 to 1094 nm). The capsules were loaded with two bioactive compounds: gallic acid (GA) and oregano essential oil (OEO). Both bioactive materials were encapsulated in FucoPol particles, retaining their antioxidant activity after the drying process. Release studies showed that GA release in simulated gastric and intestinal fluids was faster than that of OEO, envisaging that the latter had established stronger interactions with the polymer matrix. These results suggest that FucoPol has a good potential for use as encapsulating material of bioactive compounds for application in several areas, including food, cosmetic or pharmaceutical products.
AB - The potential of a bacterial exopolysaccharide named FucoPol, produced by the bacterium Enterobacter A47, as encapsulation matrix was explored. Spherical capsules with a smooth surface were produced by spray drying. The obtained microcapsules had average diameters ranging from 0.5 to 26.7 μm and presented thin walls (thickness from 222 to 1094 nm). The capsules were loaded with two bioactive compounds: gallic acid (GA) and oregano essential oil (OEO). Both bioactive materials were encapsulated in FucoPol particles, retaining their antioxidant activity after the drying process. Release studies showed that GA release in simulated gastric and intestinal fluids was faster than that of OEO, envisaging that the latter had established stronger interactions with the polymer matrix. These results suggest that FucoPol has a good potential for use as encapsulating material of bioactive compounds for application in several areas, including food, cosmetic or pharmaceutical products.
KW - FucoPol
KW - Gallic acid
KW - Microencapsulation
KW - Oregano essential oil
KW - Spray drying
UR - http://www.scopus.com/inward/record.url?scp=85022053318&partnerID=8YFLogxK
U2 - 10.1016/j.ijbiomac.2017.07.023
DO - 10.1016/j.ijbiomac.2017.07.023
M3 - Article
C2 - 28687391
AN - SCOPUS:85022053318
SN - 0141-8130
VL - 104
SP - 1099
EP - 1106
JO - International Journal of Biological Macromolecules
JF - International Journal of Biological Macromolecules
ER -