Unexpected Reactivity of Trifluoromethylated Olefins with Indole: A Mechanistic Investigation

Maria Manuel Martinho Sequeira Barata Marques; António Gil de Oliveira Santos

doi:10.1016/j.tetlet.2012.02.055

Unexpected Reactivity of Trifluoromethylated Olefins with Indole: A Mechanistic Investigation

Maria Manuel Martinho Sequeira Barata Marques, António Gil de Oliveira Santos

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Several trifluoromethylated compounds were reacted with indole sodium salt, leading to monofluorinated compounds. The unexpected products formation was rationalized by DFT calculations. (C) 2012 Elsevier Ltd. All rights reserved.

Original language	Unknown
Pages (from-to)	2132-2136
Journal	Tetrahedron Letters
Volume	53
Issue number	NA
DOIs	https://doi.org/10.1016/j.tetlet.2012.02.055
Publication status	Published - 1 Jan 2012

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10.1016/j.tetlet.2012.02.055

Cite this

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title = "Unexpected Reactivity of Trifluoromethylated Olefins with Indole: A Mechanistic Investigation",

abstract = "Several trifluoromethylated compounds were reacted with indole sodium salt, leading to monofluorinated compounds. The unexpected products formation was rationalized by DFT calculations. (C) 2012 Elsevier Ltd. All rights reserved.",

author = "Marques, \{Maria Manuel Martinho Sequeira Barata\} and Santos, \{Ant{\'o}nio Gil de Oliveira\}",

year = "2012",

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AU - Santos, António Gil de Oliveira

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N2 - Several trifluoromethylated compounds were reacted with indole sodium salt, leading to monofluorinated compounds. The unexpected products formation was rationalized by DFT calculations. (C) 2012 Elsevier Ltd. All rights reserved.

AB - Several trifluoromethylated compounds were reacted with indole sodium salt, leading to monofluorinated compounds. The unexpected products formation was rationalized by DFT calculations. (C) 2012 Elsevier Ltd. All rights reserved.

U2 - 10.1016/j.tetlet.2012.02.055

DO - 10.1016/j.tetlet.2012.02.055

M3 - Article

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VL - 53

SP - 2132

EP - 2136

JO - Tetrahedron Letters

JF - Tetrahedron Letters

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