Abstract
Objectives: To assess the impact of Atopic Dermatitis (AD), including the health
status/QoL of patients, as well as the social, labor, economic effects of the disease in the Portuguese population. Methods: A comprehensive online survey was sent to AD patients. Data collected on demographics, lifestyle habits, daily life activities, working habits, disease indexes and healthcare utilization, health status/QoL indicators, EQ-5D and DLQI scales. Generalized linear models were adjusted to identify the factors influencing the economic impact of the disease and the cost for the NHS. 204 patients (64% female) responded the survey. Results: Health status is estimated at 75 (56 for severe forms, VAS scale) and DLQI 9.4 (18.7 for severe forms). More than 1/3 of the patients felt difficulties in performing daily activities and showed relevant social/emotional impacts. Severe cases revealed sleep disturbance for more than 14 nights per month. Each patient spends an average 287 hours per year on self-care and hospital visits due to their disease. Number of lost working days per year due to absenteeism or presenteeism is 52 per patient. Annual cost per patient (out-ofpocket) in health products and services is 1.818V. Considering an estimated prevalence of 440.000 patients with AD in Portugal, the annual economic impact measure
through the participation in labor market is 1.477 millionV and the estimated value of health status degradation is 1.359 millionV (willing-to-pay). Investment performed by the NHS and patients amounts more than 1.000 millionV per year
showing a positive ROI of 35% (through labor market) and 21% (willing-to-pay).
Conclusions: AD has a major impact in the daily life of patients, work, school presenteeism, productivity, social relationships and leisure activities. Cost burden to the patients is significant (80%) when compared to NHS costs. The investment from patients and NHS on the disease shows a positive ROI (never bellow 20%) from the societal perspective.
status/QoL of patients, as well as the social, labor, economic effects of the disease in the Portuguese population. Methods: A comprehensive online survey was sent to AD patients. Data collected on demographics, lifestyle habits, daily life activities, working habits, disease indexes and healthcare utilization, health status/QoL indicators, EQ-5D and DLQI scales. Generalized linear models were adjusted to identify the factors influencing the economic impact of the disease and the cost for the NHS. 204 patients (64% female) responded the survey. Results: Health status is estimated at 75 (56 for severe forms, VAS scale) and DLQI 9.4 (18.7 for severe forms). More than 1/3 of the patients felt difficulties in performing daily activities and showed relevant social/emotional impacts. Severe cases revealed sleep disturbance for more than 14 nights per month. Each patient spends an average 287 hours per year on self-care and hospital visits due to their disease. Number of lost working days per year due to absenteeism or presenteeism is 52 per patient. Annual cost per patient (out-ofpocket) in health products and services is 1.818V. Considering an estimated prevalence of 440.000 patients with AD in Portugal, the annual economic impact measure
through the participation in labor market is 1.477 millionV and the estimated value of health status degradation is 1.359 millionV (willing-to-pay). Investment performed by the NHS and patients amounts more than 1.000 millionV per year
showing a positive ROI of 35% (through labor market) and 21% (willing-to-pay).
Conclusions: AD has a major impact in the daily life of patients, work, school presenteeism, productivity, social relationships and leisure activities. Cost burden to the patients is significant (80%) when compared to NHS costs. The investment from patients and NHS on the disease shows a positive ROI (never bellow 20%) from the societal perspective.
| Original language | English |
|---|---|
| Article number | POSB368 |
| Pages (from-to) | S232-S232 |
| Number of pages | 1 |
| Journal | Value In Health |
| Volume | 25 |
| Issue number | Supl. 1 |
| DOIs | |
| Publication status | Published - 1 Jan 2022 |
| Event | Virtual ISPOR Europe 2021, "Emerging Frontiers and Opportunities: Special Populations and Technologies” - Virtual Duration: 30 Nov 2021 → 3 Dec 2021 |
