Tumor start-up: mitochondrial fusion makes it happen

Research output: Contribution to journalComment/debatepeer-review

1 Citation (Scopus)


Whether changes in cellular metabolism precede tumor formation and trigger malignant properties or simply serve as a bioenergetic adaptation of cancer during disease progression remains debated. Bonnay et al (2020) now show that a metabolic reprogramming toward increased oxidative phosphorylation is required for irreversible cell immortalization and subsequent tumor formation.

Original languageEnglish
Article numbere106927
JournalEmbo Journal
Issue number23
Early online date31 Oct 2020
Publication statusPublished - 1 Dec 2020


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