TY - JOUR
T1 - Tuberculose extensivamente resistente: uma realidade presente. Revisão da literatura a propósito de um caso clínico.
AU - Morais, Sandra A.
AU - Moneti , Virginia
AU - Silva, Joana
AU - Pereira, Karen
AU - Manso, Marta
AU - Santos, Teresa Vilaça
AU - Falcão, Vera
AU - Miranda , Ana Cláudia
AU - Antunes, , Isabel
AU - Machado, Diana Isabel Oliveira
AU - Viveiros, M
AU - Rijo, , João
AU - Batista, Judite
AU - Mansinho, Kamal
PY - 2017
Y1 - 2017
N2 - Decades after tuberculosis having acquired the status of curable disease, the emergence of Mycobacterium tuberculosis strains resistant to the most effective anti-tuberculosis drugs used in first-line treatment have placed this disease again as a global threat to public health. The epidemiology, pathogenesis, diagnosis and approach of drug-resistant tuberculosis in Portugal and in the world are discussed. Based on a description of a clinical case, this review highlights the difficulty and complexity of the clinical management of multi-drug resistant and extensively drugresistant tuberculosis in Portugal, a country recently considered of low incidence.
AB - Decades after tuberculosis having acquired the status of curable disease, the emergence of Mycobacterium tuberculosis strains resistant to the most effective anti-tuberculosis drugs used in first-line treatment have placed this disease again as a global threat to public health. The epidemiology, pathogenesis, diagnosis and approach of drug-resistant tuberculosis in Portugal and in the world are discussed. Based on a description of a clinical case, this review highlights the difficulty and complexity of the clinical management of multi-drug resistant and extensively drugresistant tuberculosis in Portugal, a country recently considered of low incidence.
M3 - Article
SN - 0870-1571
VL - 13
SP - 24
EP - 34
JO - Revista Portuguesa de Doenças Infecciosas
JF - Revista Portuguesa de Doenças Infecciosas
IS - 1
ER -