Towards single cell spectroscopy and refractometry in microfluidic chip platforms

Hugo Manuel Brito Águas; Abel Martin Oliva

doi:10.1117/12.892180

Towards single cell spectroscopy and refractometry in microfluidic chip platforms

Hugo Manuel Brito Águas, Abel Martin Oliva

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

1 Citation (Scopus)

Abstract

This paper evaluates various strategies proposed for single cell refractometry and spectroscopy using fiber optic sensors and microfluidic chips. Details concerning design, fabrication and characterization of the chips will be addressed. Preliminary results obtained with alternative on-chip configurations using combination of fiber Bragg gratings with mirrored single mode and multimode fibers will be presented indicating the possibility of performing simultaneous assessment of cellular refractive index and absorption properties.

Original language	Unknown
Title of host publication	SPIE Proceedings
Pages	800122
Volume	8001
DOIs	https://doi.org/10.1117/12.892180
Publication status	Published - 1 Jan 2011
Event	International Conference on Applications of Optics and Photonics - Braga, Portugal Duration: 3 May 2011 → 7 May 2011

Conference

Conference	International Conference on Applications of Optics and Photonics
Country/Territory	Portugal
City	Braga
Period	3/05/11 → 7/05/11

Access to Document

10.1117/12.892180

Cite this

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title = "Towards single cell spectroscopy and refractometry in microfluidic chip platforms",

abstract = "This paper evaluates various strategies proposed for single cell refractometry and spectroscopy using fiber optic sensors and microfluidic chips. Details concerning design, fabrication and characterization of the chips will be addressed. Preliminary results obtained with alternative on-chip configurations using combination of fiber Bragg gratings with mirrored single mode and multimode fibers will be presented indicating the possibility of performing simultaneous assessment of cellular refractive index and absorption properties.",

keywords = "Fabry-Perot cavity, microfluidics, single cell analysis, spectroscopy, optical fiber sensors",

author = "{\'A}guas, {Hugo Manuel Brito} and Oliva, {Abel Martin}",

year = "2011",

month = jan,

day = "1",

doi = "10.1117/12.892180",

language = "Unknown",

isbn = "9780819485755",

volume = "8001",

pages = "800122",

booktitle = "SPIE Proceedings",

note = "International Conference on Applications of Optics and Photonics ; Conference date: 03-05-2011 Through 07-05-2011",

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T1 - Towards single cell spectroscopy and refractometry in microfluidic chip platforms

AU - Águas, Hugo Manuel Brito

AU - Oliva, Abel Martin

PY - 2011/1/1

Y1 - 2011/1/1

N2 - This paper evaluates various strategies proposed for single cell refractometry and spectroscopy using fiber optic sensors and microfluidic chips. Details concerning design, fabrication and characterization of the chips will be addressed. Preliminary results obtained with alternative on-chip configurations using combination of fiber Bragg gratings with mirrored single mode and multimode fibers will be presented indicating the possibility of performing simultaneous assessment of cellular refractive index and absorption properties.

AB - This paper evaluates various strategies proposed for single cell refractometry and spectroscopy using fiber optic sensors and microfluidic chips. Details concerning design, fabrication and characterization of the chips will be addressed. Preliminary results obtained with alternative on-chip configurations using combination of fiber Bragg gratings with mirrored single mode and multimode fibers will be presented indicating the possibility of performing simultaneous assessment of cellular refractive index and absorption properties.

KW - Fabry-Perot cavity

KW - microfluidics

KW - single cell analysis

KW - spectroscopy

KW - optical fiber sensors

U2 - 10.1117/12.892180

DO - 10.1117/12.892180

M3 - Conference contribution

SN - 9780819485755

VL - 8001

SP - 800122

BT - SPIE Proceedings

T2 - International Conference on Applications of Optics and Photonics

Y2 - 3 May 2011 through 7 May 2011

ER -