TOFPET 2: A high-performance circuit for PET time-of-flight

Agostino Di Francesco, Ricardo Bugalho, Luis Oliveira, Angelo Rivetti, Manuel Rolo, José Carlos da Silva, Joao Varela

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


We present a readout and digitization ASIC featuring low-noise and low-power for time-of flight (TOF) applications using SiPMs. The circuit is designed in standard CMOS 110 nm technology, has 64 independent channels and is optimized for time-of-flight measurement in Positron Emission Tomography (TOF-PET). The input amplifier is a low impedance current conveyor based on a regulated common-gate topology. Each channel has quad-buffered analogue interpolation TDCs (time binning 20 ps) and charge integration ADCs with linear response at full scale (1500 pC). The signal amplitude can also be derived from the measurement of time-over-threshold (ToT). Simulation results show that for a single photo-electron signal with charge 200 (550) fC generated by a SiPM with (320 pF) capacitance the circuit has 24 (30) dB SNR, 75 (39) ps r.m.s. resolution, and 4 (8) mW power consumption. The event rate is 600 kHz per channel, with up to 2 MHz dark counts rejection.

Original languageEnglish
Pages (from-to)194-195
Number of pages2
JournalNuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Publication statusPublished - 11 Jul 2016


  • Applications
  • ASIC
  • Electronics
  • Front-end
  • PET


Dive into the research topics of 'TOFPET 2: A high-performance circuit for PET time-of-flight'. Together they form a unique fingerprint.

Cite this