Thrombus aspiration in patients with ST-elevation myocardial infarction: Results of a national registry of interventional cardiology

Hélder Pereira, Daniel Caldeira, Rui Campante Teles, Marco Costa, Pedro Canas da Silva, Vasco da Gama Ribeiro, Vítor Brandão, Dinis Martins, Fernando Matias, Francisco Pereira-Machado, José Baptista, Pedro Farto e. Abreu, Ricardo Santos, António Drummond, Henrique Cyrne de Carvalho, João Calisto, João Carlos Silva, João Luís Pipa, Jorge Marques, Paulino SousaRenato Fernandes, Rui Cruz Ferreira, Sousa Ramos, Eduardo Infante Oliveira, Manuel de Sousa Almeida

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Abstract

Background: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. Methods: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). Results: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54-1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35-0.98; 3500 patients). Conclusions: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI.

Original languageEnglish
Article number69
JournalBMC Cardiovascular Disorders
Volume18
Issue number1
DOIs
Publication statusPublished - 24 Apr 2018

Keywords

  • Angioplasty
  • Mortality
  • Portugal
  • Primary PCI
  • Thrombectomy
  • Thrombus aspiration

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