TY - JOUR
T1 - Thrombus aspiration in patients with ST-elevation myocardial infarction
T2 - Results of a national registry of interventional cardiology
AU - Pereira, Hélder
AU - Caldeira, Daniel
AU - Teles, Rui Campante
AU - Costa, Marco
AU - da Silva, Pedro Canas
AU - da Gama Ribeiro, Vasco
AU - Brandão, Vítor
AU - Martins, Dinis
AU - Matias, Fernando
AU - Pereira-Machado, Francisco
AU - Baptista, José
AU - Abreu, Pedro Farto e.
AU - Santos, Ricardo
AU - Drummond, António
AU - de Carvalho, Henrique Cyrne
AU - Calisto, João
AU - Silva, João Carlos
AU - Pipa, João Luís
AU - Marques, Jorge
AU - Sousa, Paulino
AU - Fernandes, Renato
AU - Ferreira, Rui Cruz
AU - Ramos, Sousa
AU - Oliveira, Eduardo Infante
AU - de Sousa Almeida, Manuel
PY - 2018/4/24
Y1 - 2018/4/24
N2 - Background: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. Methods: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). Results: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54-1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35-0.98; 3500 patients). Conclusions: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI.
AB - Background: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. Methods: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality, was analysed through adjusted odds ratio (aOR) and 95% confidence intervals (95%CI). Results: We assessed data for 9458 STEMI patients that undergone P-PCI (35% treated with TA). The risk of in-hospital mortality with TA (aOR 0.93, 95%CI:0.54-1.60) was not significantly decreased. After matching patients through the propensity score, TA reduced significantly the risk of in-hospital mortality (OR 0.58, 95%CI:0.35-0.98; 3500 patients). Conclusions: The whole cohort data does not support the routine use of TA in P-PCI, but the results of the propensity-score matched cohort suggests that the use of selective TA may improve the short-term risks of STEMI.
KW - Angioplasty
KW - Mortality
KW - Portugal
KW - Primary PCI
KW - Thrombectomy
KW - Thrombus aspiration
UR - http://www.scopus.com/inward/record.url?scp=85046009523&partnerID=8YFLogxK
U2 - 10.1186/s12872-018-0794-4
DO - 10.1186/s12872-018-0794-4
M3 - Article
C2 - 29699478
AN - SCOPUS:85046009523
SN - 1471-2261
VL - 18
JO - BMC Cardiovascular Disorders
JF - BMC Cardiovascular Disorders
IS - 1
M1 - 69
ER -