TY - JOUR
T1 - Thermal, Structural, Morphological and Electrical Characterization of Cerium-Containing 45S5 for Metal Implant Coatings
AU - Gavinho, Sílvia Rodrigues
AU - Melo, Bruno Miguel Gonçalves
AU - Borges, João Paulo
AU - Silva, Jorge Carvalho
AU - Graça, Manuel Pedro Fernandes
N1 - Funding Information:
info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50025%2F2020/PT#
info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50025%2F2020/PT#
info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04378%2F2020/PT#
info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04378%2F2020/PT#
info:eu-repo/grantAgreement/FCT/POR_CENTRO/SFRH%2FBD%2F148233%2F2019/PT#
info:eu-repo/grantAgreement/FCT/POR_CENTRO/SFRH%2FBD%2F117487%2F2016/PT#
The authors extend their appreciation to the FEDER funds through the COMPETE 2020 Program and National Funds through FCT—Portuguese Foundation for Science and Technology under the project LISBOA-01-0247-FEDER-039985/POCI-01-0247-FEDER-039985, LA/P/0037/2020.
Publisher Copyright:
© 2023 by the authors.
PY - 2023/1/28
Y1 - 2023/1/28
N2 - Biomaterial coatings on dental implants are increasingly being used as a solution to the problems of rejection and implant loss. Bioglass® has been seen as a promising material for coating metal implants, increasing the integration rate and improving the bond between the bone and the implant. Multifunctional bioactive glasses can exhibit antibacterial, antitumor and antioxidant effects with the addition of therapeutic ions. The cerium ion has shown an antioxidant effect through mimicking mechanisms and by acting as a scavenger of reactive oxygen species (ROS), which is important for avoiding oxidative stress post-surgery. Furthermore, it is possible to store electrical charge on the bioglass surface, which potentiates osseointegration. In this work, glasses with various percentages of cerium oxide (0.25, 0.5, 1 and 2 mol%) were developed and structurally and electrically analyzed. It was verified that the cerium insertion did not modify the amorphous phase characteristic of the glass but showed an increase in the number of non-bridging oxygens (NBOs). This increase in NBOs did not modify the electrical conductivity in either the ac or dc regime. The similar permittivity values of the glasses also suggest that their storage ability is unchanged with the addition of CeO2. Concerning the impedance spectroscopy (IS) data, a decrease in resistance is visible with the addition of cerium oxide, suggesting a favorable behavior for applications as an antioxidant through the electro-Fenton reaction.
AB - Biomaterial coatings on dental implants are increasingly being used as a solution to the problems of rejection and implant loss. Bioglass® has been seen as a promising material for coating metal implants, increasing the integration rate and improving the bond between the bone and the implant. Multifunctional bioactive glasses can exhibit antibacterial, antitumor and antioxidant effects with the addition of therapeutic ions. The cerium ion has shown an antioxidant effect through mimicking mechanisms and by acting as a scavenger of reactive oxygen species (ROS), which is important for avoiding oxidative stress post-surgery. Furthermore, it is possible to store electrical charge on the bioglass surface, which potentiates osseointegration. In this work, glasses with various percentages of cerium oxide (0.25, 0.5, 1 and 2 mol%) were developed and structurally and electrically analyzed. It was verified that the cerium insertion did not modify the amorphous phase characteristic of the glass but showed an increase in the number of non-bridging oxygens (NBOs). This increase in NBOs did not modify the electrical conductivity in either the ac or dc regime. The similar permittivity values of the glasses also suggest that their storage ability is unchanged with the addition of CeO2. Concerning the impedance spectroscopy (IS) data, a decrease in resistance is visible with the addition of cerium oxide, suggesting a favorable behavior for applications as an antioxidant through the electro-Fenton reaction.
KW - antioxidant effect
KW - Bioglass
KW - cerium
KW - dielectric properties
KW - implant coatings
KW - osteointegration
UR - http://www.scopus.com/inward/record.url?scp=85149066080&partnerID=8YFLogxK
U2 - 10.3390/coatings13020294
DO - 10.3390/coatings13020294
M3 - Article
AN - SCOPUS:85149066080
SN - 2079-6412
VL - 13
JO - COATINGS
JF - COATINGS
IS - 2
M1 - 294
ER -