The role of Spongia Sp. In the discovery of marine lead compounds

P. Maximo; Luísa M. Ferreira; Paula Branco; Pedro Lima; Ana Lourenço

doi:10.3390/md14080139

The role of Spongia Sp. In the discovery of marine lead compounds

P. Maximo, Luísa M. Ferreira, Paula Branco, Pedro Lima, Ana Lourenço

Research output: Contribution to journal › Review article › peer-review

21 Citations (Scopus)

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Abstract

A comprehensive review on the chemistry of Spongia sp. is here presented, together with the biological activity of the isolated compounds. The compounds are grouped in sesquiterpene quinones, diterpenes, C21 and other linear furanoterpenes, sesterterpenes, sterols (including secosterols), macrolides and miscellaneous compounds. Among other reports we include studies on the intraspecific diversity of a Mediterranean species, compounds isolated from associated sponge and nudibranch and compounds isolated from S. zimocca and the red seaweed Laurentia microcladia. Under biological activity a table of the reported biological activities of the various compounds and the biological screening of extracts are described. The present review covers the literature from 1971 to 2015.

Original language	English
Article number	139
Journal	Marine Drugs
Volume	14
Issue number	8
DOIs	https://doi.org/10.3390/md14080139
Publication status	Published - 1 Aug 2016

Keywords

Biological activity
C21 furanoterpenes
Diterpenes
Macrolides
Sesquiterpene quinones
Sesterterpenes
Spongia sp.
Sterols

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/md14080139Licence: CC BY

The Role of Spongia sp. in the Discovery of Marine Lead CompoundsFinal published version, 31.7 MBLicence: CC BY

Cite this

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title = "The role of Spongia Sp. In the discovery of marine lead compounds",

abstract = "A comprehensive review on the chemistry of Spongia sp. is here presented, together with the biological activity of the isolated compounds. The compounds are grouped in sesquiterpene quinones, diterpenes, C21 and other linear furanoterpenes, sesterterpenes, sterols (including secosterols), macrolides and miscellaneous compounds. Among other reports we include studies on the intraspecific diversity of a Mediterranean species, compounds isolated from associated sponge and nudibranch and compounds isolated from S. zimocca and the red seaweed Laurentia microcladia. Under biological activity a table of the reported biological activities of the various compounds and the biological screening of extracts are described. The present review covers the literature from 1971 to 2015.",

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AU - Ferreira, Luísa M.

AU - Branco, Paula

AU - Lima, Pedro

AU - Lourenço, Ana

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AB - A comprehensive review on the chemistry of Spongia sp. is here presented, together with the biological activity of the isolated compounds. The compounds are grouped in sesquiterpene quinones, diterpenes, C21 and other linear furanoterpenes, sesterterpenes, sterols (including secosterols), macrolides and miscellaneous compounds. Among other reports we include studies on the intraspecific diversity of a Mediterranean species, compounds isolated from associated sponge and nudibranch and compounds isolated from S. zimocca and the red seaweed Laurentia microcladia. Under biological activity a table of the reported biological activities of the various compounds and the biological screening of extracts are described. The present review covers the literature from 1971 to 2015.

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KW - Diterpenes

KW - Macrolides

KW - Sesquiterpene quinones

KW - Sesterterpenes

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KW - Sterols

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The role of Spongia Sp. In the discovery of marine lead compounds

Abstract

Keywords

UN SDGs

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