The role of ribonucleases and sRNAs in the virulence of foodborne pathogens

Rute G. Matos, Jorge Casinhas, Cátia Bárria, Ricardo F. Dos Santos, Inês J. Silva, Cecília M. Arraiano

Research output: Contribution to journalShort surveypeer-review

10 Citations (Scopus)

Abstract

Contaminated food is the source of many severe infections in humans. Recent advances in food science have discovered new foodborne pathogens and progressed in characterizing their biology, life cycle, and infection processes. All this knowledge has been contributing to prevent food contamination, and to develop new therapeutics to treat the infections caused by these pathogens. RNA metabolism is a crucial biological process and has an enormous potential to offer new strategies to fight foodborne pathogens. In this review, we will summarize what is known about the role of bacterial ribonucleases and sRNAs in the virulence of several foodborne pathogens and how can we use that knowledge to prevent infection.

Original languageEnglish
Article number910
JournalFrontiers in Microbiology
Volume8
Issue numberMAY
DOIs
Publication statusPublished - 19 May 2017

Keywords

  • Control of gene expression
  • Foodborne pathogens
  • PNPase
  • RNA metabolism
  • RNase E
  • RNase III
  • RNase R
  • YbeY

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