Papel da oximetria nocturna no rastreio da síndroma de apneia-hipopneia obstrutiva do sono

Translated title of the contribution: The role of nocturnal oximetry in obstructive sleep apnoea-hypopnoea syndrome screening

Celestina Ventura, Ana Sofia Oliveira, Rita Dias, Joana Teixeira, Cristina Canhão, Odete Santos, Paula Pinto, Cristina Bárbara

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Aim: The aim of our study was to evaluate the sensitivity and specificity of Nocturnal Oximetry (NO) as a diagnostic Screening tool for obstructive sleep apnoea hypopnoea syndrome (OSAHS), compared with polysomnography (PSG) as the gold standard. Methodology: 63 patients with clinical suspicion of OSAHS and exclusion of respiratory disease underwent PSG and NO. We then determined NO sensitivity, specificity, positive (PPV) and negative predictive values (NPV). Results: OSAHS was diagnosed in 47 patients with a mean age of 54 years. In the evaluation of the percentage of Total Sleep Time (TST) with oxygen desaturation below 90%, we found significant differences between patients with OSAHS (25.4 ± 29.7%) and without OSAHS (1 ± 1.5%), p<0,001. We used two cutoff points to evaluate sensitivity, specificity, positive (PPV) and negative predictive values (NPV), based on the severity of O 2 desaturation (StO 2 <90%). Using the first cutoff point we diagnosed with NO as positive all the patients with TST desaturation values ≥1% of the TST. Under these circumstances we found a sensitivity of 76.6%, a specificity of 75%, a PPV of 90% and an NPV value of 52.2% for our screening test (NO). Using the second cutoff point, we diagnosed with NO as positive all the patients with TST desaturation values ≥5% of the TST. With this method we found a sensitivity of 65.9%, a specificity of 100%, a PPV of 100% and an NPV of 50%. Conclusion: NO is a useful screening test for the diagnosis of OSAHS in patients without respiratory disease.

Original languagePortuguese
Pages (from-to)525-551
Number of pages27
JournalRevista Portuguesa de Pneumologia
Volume13
Issue number4
Publication statusPublished - 1 Jan 2007

Fingerprint

Oximetry
Obstructive Sleep Apnea
Sleep
Polysomnography
Sensitivity and Specificity

Keywords

  • Nocturnal oximetry
  • Obstructive sleep apnoea hypopnoea syndrome

Cite this

Ventura, C., Oliveira, A. S., Dias, R., Teixeira, J., Canhão, C., Santos, O., ... Bárbara, C. (2007). Papel da oximetria nocturna no rastreio da síndroma de apneia-hipopneia obstrutiva do sono. Revista Portuguesa de Pneumologia, 13(4), 525-551.
Ventura, Celestina ; Oliveira, Ana Sofia ; Dias, Rita ; Teixeira, Joana ; Canhão, Cristina ; Santos, Odete ; Pinto, Paula ; Bárbara, Cristina. / Papel da oximetria nocturna no rastreio da síndroma de apneia-hipopneia obstrutiva do sono. In: Revista Portuguesa de Pneumologia. 2007 ; Vol. 13, No. 4. pp. 525-551.
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abstract = "Aim: The aim of our study was to evaluate the sensitivity and specificity of Nocturnal Oximetry (NO) as a diagnostic Screening tool for obstructive sleep apnoea hypopnoea syndrome (OSAHS), compared with polysomnography (PSG) as the gold standard. Methodology: 63 patients with clinical suspicion of OSAHS and exclusion of respiratory disease underwent PSG and NO. We then determined NO sensitivity, specificity, positive (PPV) and negative predictive values (NPV). Results: OSAHS was diagnosed in 47 patients with a mean age of 54 years. In the evaluation of the percentage of Total Sleep Time (TST) with oxygen desaturation below 90{\%}, we found significant differences between patients with OSAHS (25.4 ± 29.7{\%}) and without OSAHS (1 ± 1.5{\%}), p<0,001. We used two cutoff points to evaluate sensitivity, specificity, positive (PPV) and negative predictive values (NPV), based on the severity of O 2 desaturation (StO 2 <90{\%}). Using the first cutoff point we diagnosed with NO as positive all the patients with TST desaturation values ≥1{\%} of the TST. Under these circumstances we found a sensitivity of 76.6{\%}, a specificity of 75{\%}, a PPV of 90{\%} and an NPV value of 52.2{\%} for our screening test (NO). Using the second cutoff point, we diagnosed with NO as positive all the patients with TST desaturation values ≥5{\%} of the TST. With this method we found a sensitivity of 65.9{\%}, a specificity of 100{\%}, a PPV of 100{\%} and an NPV of 50{\%}. Conclusion: NO is a useful screening test for the diagnosis of OSAHS in patients without respiratory disease.",
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Ventura, C, Oliveira, AS, Dias, R, Teixeira, J, Canhão, C, Santos, O, Pinto, P & Bárbara, C 2007, 'Papel da oximetria nocturna no rastreio da síndroma de apneia-hipopneia obstrutiva do sono', Revista Portuguesa de Pneumologia, vol. 13, no. 4, pp. 525-551.

Papel da oximetria nocturna no rastreio da síndroma de apneia-hipopneia obstrutiva do sono. / Ventura, Celestina; Oliveira, Ana Sofia; Dias, Rita; Teixeira, Joana; Canhão, Cristina; Santos, Odete; Pinto, Paula; Bárbara, Cristina.

In: Revista Portuguesa de Pneumologia, Vol. 13, No. 4, 01.01.2007, p. 525-551.

Research output: Contribution to journalArticle

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T1 - Papel da oximetria nocturna no rastreio da síndroma de apneia-hipopneia obstrutiva do sono

AU - Ventura, Celestina

AU - Oliveira, Ana Sofia

AU - Dias, Rita

AU - Teixeira, Joana

AU - Canhão, Cristina

AU - Santos, Odete

AU - Pinto, Paula

AU - Bárbara, Cristina

PY - 2007/1/1

Y1 - 2007/1/1

N2 - Aim: The aim of our study was to evaluate the sensitivity and specificity of Nocturnal Oximetry (NO) as a diagnostic Screening tool for obstructive sleep apnoea hypopnoea syndrome (OSAHS), compared with polysomnography (PSG) as the gold standard. Methodology: 63 patients with clinical suspicion of OSAHS and exclusion of respiratory disease underwent PSG and NO. We then determined NO sensitivity, specificity, positive (PPV) and negative predictive values (NPV). Results: OSAHS was diagnosed in 47 patients with a mean age of 54 years. In the evaluation of the percentage of Total Sleep Time (TST) with oxygen desaturation below 90%, we found significant differences between patients with OSAHS (25.4 ± 29.7%) and without OSAHS (1 ± 1.5%), p<0,001. We used two cutoff points to evaluate sensitivity, specificity, positive (PPV) and negative predictive values (NPV), based on the severity of O 2 desaturation (StO 2 <90%). Using the first cutoff point we diagnosed with NO as positive all the patients with TST desaturation values ≥1% of the TST. Under these circumstances we found a sensitivity of 76.6%, a specificity of 75%, a PPV of 90% and an NPV value of 52.2% for our screening test (NO). Using the second cutoff point, we diagnosed with NO as positive all the patients with TST desaturation values ≥5% of the TST. With this method we found a sensitivity of 65.9%, a specificity of 100%, a PPV of 100% and an NPV of 50%. Conclusion: NO is a useful screening test for the diagnosis of OSAHS in patients without respiratory disease.

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KW - Obstructive sleep apnoea hypopnoea syndrome

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Ventura C, Oliveira AS, Dias R, Teixeira J, Canhão C, Santos O et al. Papel da oximetria nocturna no rastreio da síndroma de apneia-hipopneia obstrutiva do sono. Revista Portuguesa de Pneumologia. 2007 Jan 1;13(4):525-551.