The minimum information required for a glycomics experiment (MIRAGE) project: Improving the standards for reporting glycan microarray-based data

Yan Liu, Ryan McBride, Mark Stoll, Maria Angelina de Sá Palma, Lisete Silva, Sanjay Agravat, Kiyoko F. Aoki-Kinoshita, Matthew P. Campbell, Catherine E. Costello, Anne Dell, Stuart M. Haslam, Niclas G. Karlsson, Kay Hooi Khoo, Daniel Kolarich, Milos V. Novotny, Nicolle H. Packer, Rene Ranzinger, Erdmann Rapp, Pauline M. Rudd, Weston B. StruweMichael Tiemeyer, Lance Wells, William S. York, Joseph Zaia, Carsten Kettner, James C. Paulson, Ten Feizi, David F. Smith

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

MIRAGE (Minimum Information Required for A Glycomics Experiment) is an initiative that was created by experts in the fields of glycobiology, glycoanalytics and glycoinformatics to produce guidelines for reporting results from the diverse types of experiments and analyses used in structural and functional studies of glycans in the scientific literature. As a sequel to the guidelines for sample preparation (Struwe et al. 2016, Glycobiology, 26:907-910) and mass spectrometry data (Kolarich et al. 2013, Mol. Cell Proteomics, 12:991-995), here we present the first version of guidelines intended to improve the standards for reporting data from glycan microarray analyses. For each of eight areas in the workflow of a glycan microarray experiment, we provide guidelines for the minimal information that should be provided in reporting results. We hope that the MIRAGE glycan microarray guidelines proposed here will gain broad acceptance by the community, and will facilitate interpretation and reproducibility of the glycan microarray results with implications in comparison of data from different laboratories and eventual deposition of glycan microarray data in international databases.

Original languageEnglish
Pages (from-to)280-284
Number of pages5
JournalGlycobiology
Volume27
Issue number4
DOIs
Publication statusPublished - 2017

Keywords

  • Glycan microarrays
  • Glycans
  • Glycobiology
  • Glycomics
  • MIRAGE

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