TY - JOUR
T1 - The impact of different types of shift work on blood pressure and hypertension
T2 - A systematic review and meta-analysis
AU - Madeira, Sara Gamboa
AU - Fernandes, Carina
AU - Paiva, Teresa
AU - Moreira, Carlos Santos
AU - Caldeira, Daniel
N1 - Funding Information:
This work was supported by the Ph.D. research Grant PDE/BDE/127787/2016 from Funda??o para a Ci?ncia e Tecnologia (FCT) /Fundo Social Europeu.
Funding Information:
Funding: This work was supported by the Ph.D. research Grant PDE/BDE/127787/2016 from Fundação para a Ciência e Tecnologia (FCT) /Fundo Social Europeu.
Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/7/1
Y1 - 2021/7/1
N2 - Shift work (SW) encompasses 20% of the European workforce. Moreover, high blood pressure (BP) remains a leading cause of death globally. This review aimed to synthesize the magnitude of the potential impact of SW on systolic blood pressure (SBP), diastolic blood pressure (DBP) and hypertension (HTN). MEDLINE, EMBASE and CENTRAL databases were searched for epidemiological studies evaluating BP and/or HTN diagnosis among shift workers, compared with day workers. Random-effects meta-analyses were performed and the results were expressed as pooled mean differences or odds ratios and 95% confidence intervals (95% CI). The Newcastle–Ottawa Scale was used to assess the risk of bias. Forty-five studies were included, involving 117,252 workers. We found a significant increase in both SBD and DBP among permanent night workers (2.52 mmHg, 95% CI 0.75–4.29 and 1.76 mmHg, 95% CI 0.41–3.12, respectively). For rotational shift workers, both with and without night work, we found a significant increase but only for SBP (0.65 mmHg, 95% CI 0.07–1.22 and 1.28 mmHg, 95% CI 0.18–2.39, respectively). No differences were found for HTN. Our findings suggest that SW is associated with an increase of BP, mainly for permanent night workers and for SBP. This is of special interest given the large number of susceptible workers exposed over time.
AB - Shift work (SW) encompasses 20% of the European workforce. Moreover, high blood pressure (BP) remains a leading cause of death globally. This review aimed to synthesize the magnitude of the potential impact of SW on systolic blood pressure (SBP), diastolic blood pressure (DBP) and hypertension (HTN). MEDLINE, EMBASE and CENTRAL databases were searched for epidemiological studies evaluating BP and/or HTN diagnosis among shift workers, compared with day workers. Random-effects meta-analyses were performed and the results were expressed as pooled mean differences or odds ratios and 95% confidence intervals (95% CI). The Newcastle–Ottawa Scale was used to assess the risk of bias. Forty-five studies were included, involving 117,252 workers. We found a significant increase in both SBD and DBP among permanent night workers (2.52 mmHg, 95% CI 0.75–4.29 and 1.76 mmHg, 95% CI 0.41–3.12, respectively). For rotational shift workers, both with and without night work, we found a significant increase but only for SBP (0.65 mmHg, 95% CI 0.07–1.22 and 1.28 mmHg, 95% CI 0.18–2.39, respectively). No differences were found for HTN. Our findings suggest that SW is associated with an increase of BP, mainly for permanent night workers and for SBP. This is of special interest given the large number of susceptible workers exposed over time.
KW - Blood pressure
KW - Cardiovascular disease
KW - Night shift
KW - Occupational health
KW - Permanent shift
KW - Rotating shift
KW - Systematic review
KW - Work schedule
UR - http://www.scopus.com/inward/record.url?scp=85108267929&partnerID=8YFLogxK
U2 - 10.3390/ijerph18136738
DO - 10.3390/ijerph18136738
M3 - Review article
C2 - 34201492
AN - SCOPUS:85108267929
SN - 1660-4601
VL - 18
JO - International Journal of Environmental Research and Public Health
JF - International Journal of Environmental Research and Public Health
IS - 13
M1 - 6738
ER -
