The effect of long-chain polyunsaturated fatty acids intake during pregnancy on adiposity of healthy full-term offspring at birth

L. Pereira-Da-Silva, C. Cabo, A. C. Moreira, A. L. Papoila, D. Virella, R. Neves, K. M. Bridges, G. Cordeiro-Ferreira

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

OBJECTIVE: The adjusted effect of long-chain polyunsaturated fatty acid (LCPUFA) intake during pregnancy on adiposity at birth of healthy full-term appropriate-for-gestational age neonates was evaluated. STUDY DESIGN: In a cross-sectional convenience sample of 100 mother and infant dyads, LCPUFA intake during pregnancy was assessed by food frequency questionnaire with nutrient intake calculated using Food Processor Plus. Linear regression models for neonatal body composition measurements, assessed by air displacement plethysmography and anthropometry, were adjusted for maternal LCPUFA intakes, energy and macronutrient intakes, prepregnancy body mass index and gestational weight gain. RESULT: Positive associations between maternal docosahexaenoic acid intake and ponderal index in male offspring (β = 0.165; 95% confidence interval (CI): 0.031-0.299; P = 0.017), and between n-6:n-3 LCPUFA ratio intake and fat mass (β = 0.021; 95% CI: 0.002- 0.041; P = 0.034) and percentage of fat mass (β = 0.636; 95% CI: 0.125-1.147; P = 0.016) in female offspring were found. CONCLUSION: Using a reliable validated method to assess body composition, adjusted positive associations between maternal docosahexaenoic acid intake and birth size in male offspring and between n-6:n-3 LCPUFA ratio intake and adiposity in female offspring were found, suggesting that maternal LCPUFA intake strongly influences fetal body composition.

Original languageEnglish
Pages (from-to)177-180
Number of pages4
JournalJournal of Perinatology
Volume35
Issue number3
DOIs
Publication statusPublished - 1 Mar 2015

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Adiposity
Unsaturated Fatty Acids
Parturition
Pregnancy
Mothers
Body Composition
Docosahexaenoic Acids
Confidence Intervals
Food
Linear Models
Fats
Anthropometry
Plethysmography
Energy Intake
Gestational Age
Weight Gain
Body Mass Index
Air
Newborn Infant
Weights and Measures

Cite this

Pereira-Da-Silva, L. ; Cabo, C. ; Moreira, A. C. ; Papoila, A. L. ; Virella, D. ; Neves, R. ; Bridges, K. M. ; Cordeiro-Ferreira, G. / The effect of long-chain polyunsaturated fatty acids intake during pregnancy on adiposity of healthy full-term offspring at birth. In: Journal of Perinatology. 2015 ; Vol. 35, No. 3. pp. 177-180.
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title = "The effect of long-chain polyunsaturated fatty acids intake during pregnancy on adiposity of healthy full-term offspring at birth",
abstract = "OBJECTIVE: The adjusted effect of long-chain polyunsaturated fatty acid (LCPUFA) intake during pregnancy on adiposity at birth of healthy full-term appropriate-for-gestational age neonates was evaluated. STUDY DESIGN: In a cross-sectional convenience sample of 100 mother and infant dyads, LCPUFA intake during pregnancy was assessed by food frequency questionnaire with nutrient intake calculated using Food Processor Plus. Linear regression models for neonatal body composition measurements, assessed by air displacement plethysmography and anthropometry, were adjusted for maternal LCPUFA intakes, energy and macronutrient intakes, prepregnancy body mass index and gestational weight gain. RESULT: Positive associations between maternal docosahexaenoic acid intake and ponderal index in male offspring (β = 0.165; 95{\%} confidence interval (CI): 0.031-0.299; P = 0.017), and between n-6:n-3 LCPUFA ratio intake and fat mass (β = 0.021; 95{\%} CI: 0.002- 0.041; P = 0.034) and percentage of fat mass (β = 0.636; 95{\%} CI: 0.125-1.147; P = 0.016) in female offspring were found. CONCLUSION: Using a reliable validated method to assess body composition, adjusted positive associations between maternal docosahexaenoic acid intake and birth size in male offspring and between n-6:n-3 LCPUFA ratio intake and adiposity in female offspring were found, suggesting that maternal LCPUFA intake strongly influences fetal body composition.",
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The effect of long-chain polyunsaturated fatty acids intake during pregnancy on adiposity of healthy full-term offspring at birth. / Pereira-Da-Silva, L.; Cabo, C.; Moreira, A. C.; Papoila, A. L.; Virella, D.; Neves, R.; Bridges, K. M.; Cordeiro-Ferreira, G.

In: Journal of Perinatology, Vol. 35, No. 3, 01.03.2015, p. 177-180.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The effect of long-chain polyunsaturated fatty acids intake during pregnancy on adiposity of healthy full-term offspring at birth

AU - Pereira-Da-Silva, L.

AU - Cabo, C.

AU - Moreira, A. C.

AU - Papoila, A. L.

AU - Virella, D.

AU - Neves, R.

AU - Bridges, K. M.

AU - Cordeiro-Ferreira, G.

PY - 2015/3/1

Y1 - 2015/3/1

N2 - OBJECTIVE: The adjusted effect of long-chain polyunsaturated fatty acid (LCPUFA) intake during pregnancy on adiposity at birth of healthy full-term appropriate-for-gestational age neonates was evaluated. STUDY DESIGN: In a cross-sectional convenience sample of 100 mother and infant dyads, LCPUFA intake during pregnancy was assessed by food frequency questionnaire with nutrient intake calculated using Food Processor Plus. Linear regression models for neonatal body composition measurements, assessed by air displacement plethysmography and anthropometry, were adjusted for maternal LCPUFA intakes, energy and macronutrient intakes, prepregnancy body mass index and gestational weight gain. RESULT: Positive associations between maternal docosahexaenoic acid intake and ponderal index in male offspring (β = 0.165; 95% confidence interval (CI): 0.031-0.299; P = 0.017), and between n-6:n-3 LCPUFA ratio intake and fat mass (β = 0.021; 95% CI: 0.002- 0.041; P = 0.034) and percentage of fat mass (β = 0.636; 95% CI: 0.125-1.147; P = 0.016) in female offspring were found. CONCLUSION: Using a reliable validated method to assess body composition, adjusted positive associations between maternal docosahexaenoic acid intake and birth size in male offspring and between n-6:n-3 LCPUFA ratio intake and adiposity in female offspring were found, suggesting that maternal LCPUFA intake strongly influences fetal body composition.

AB - OBJECTIVE: The adjusted effect of long-chain polyunsaturated fatty acid (LCPUFA) intake during pregnancy on adiposity at birth of healthy full-term appropriate-for-gestational age neonates was evaluated. STUDY DESIGN: In a cross-sectional convenience sample of 100 mother and infant dyads, LCPUFA intake during pregnancy was assessed by food frequency questionnaire with nutrient intake calculated using Food Processor Plus. Linear regression models for neonatal body composition measurements, assessed by air displacement plethysmography and anthropometry, were adjusted for maternal LCPUFA intakes, energy and macronutrient intakes, prepregnancy body mass index and gestational weight gain. RESULT: Positive associations between maternal docosahexaenoic acid intake and ponderal index in male offspring (β = 0.165; 95% confidence interval (CI): 0.031-0.299; P = 0.017), and between n-6:n-3 LCPUFA ratio intake and fat mass (β = 0.021; 95% CI: 0.002- 0.041; P = 0.034) and percentage of fat mass (β = 0.636; 95% CI: 0.125-1.147; P = 0.016) in female offspring were found. CONCLUSION: Using a reliable validated method to assess body composition, adjusted positive associations between maternal docosahexaenoic acid intake and birth size in male offspring and between n-6:n-3 LCPUFA ratio intake and adiposity in female offspring were found, suggesting that maternal LCPUFA intake strongly influences fetal body composition.

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DO - 10.1038/jp.2014.188

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VL - 35

SP - 177

EP - 180

JO - Journal of Perinatology

JF - Journal of Perinatology

SN - 0743-8346

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