The crystal structures of two spermadhesins reveal the CUB domain fold

Antonio Romero; Maria J. Romão; Paloma F. Varela; Ingo Kölln; Joao M. Dias; Ana L. Carvalho; Libia Sanz; Edda Töpfer-Petersen; Juan J. Calvete

doi:10.1038/nsb1097-783

The crystal structures of two spermadhesins reveal the CUB domain fold

Antonio Romero, Maria J. Romão, Paloma F. Varela, Ingo Kölln, Joao M. Dias, Ana L. Carvalho, Libia Sanz, Edda Töpfer-Petersen, Juan J. Calvete

Instituto de Tecnologia Química e Biológica António Xavier (ITQB)

Research output: Contribution to journal › Article › peer-review

133 Citations (Scopus)

Abstract

Spermadhesins, 12,000-14,000 M_r mammalian proteins, include lectins involved in sperm-egg binding and display a single CUB domain architecture. We report the crystal structures of porcine seminal plasma PSP-I/PSP-II, a heterodimer of two glycosylated spermadhesins, and bovine aSFP at 2.4 Å and 1.9 Å resolution respectively.

Original language	English
Pages (from-to)	783-788
Number of pages	6
Journal	Nature Structural Biology
Volume	4
Issue number	10
DOIs	https://doi.org/10.1038/nsb1097-783
Publication status	Published - 1 Jan 1997

Access to Document

10.1038/nsb1097-783

Cite this

@article{2a95f245623748d18b86649a372520aa,

title = "The crystal structures of two spermadhesins reveal the CUB domain fold",

abstract = "Spermadhesins, 12,000-14,000 Mr mammalian proteins, include lectins involved in sperm-egg binding and display a single CUB domain architecture. We report the crystal structures of porcine seminal plasma PSP-I/PSP-II, a heterodimer of two glycosylated spermadhesins, and bovine aSFP at 2.4 {\AA} and 1.9 {\AA} resolution respectively.",

author = "Antonio Romero and Rom{\~a}o, {Maria J.} and Varela, {Paloma F.} and Ingo K{\"o}lln and Dias, {Joao M.} and Carvalho, {Ana L.} and Libia Sanz and Edda T{\"o}pfer-Petersen and Calvete, {Juan J.}",

year = "1997",

month = jan,

day = "1",

doi = "10.1038/nsb1097-783",

language = "English",

volume = "4",

pages = "783--788",

journal = "Nature Structural Biology",

issn = "1072-8368",

publisher = "Nature Publishing Group",

number = "10",

}

TY - JOUR

T1 - The crystal structures of two spermadhesins reveal the CUB domain fold

AU - Romero, Antonio

AU - Romão, Maria J.

AU - Varela, Paloma F.

AU - Kölln, Ingo

AU - Dias, Joao M.

AU - Carvalho, Ana L.

AU - Sanz, Libia

AU - Töpfer-Petersen, Edda

AU - Calvete, Juan J.

PY - 1997/1/1

Y1 - 1997/1/1

N2 - Spermadhesins, 12,000-14,000 Mr mammalian proteins, include lectins involved in sperm-egg binding and display a single CUB domain architecture. We report the crystal structures of porcine seminal plasma PSP-I/PSP-II, a heterodimer of two glycosylated spermadhesins, and bovine aSFP at 2.4 Å and 1.9 Å resolution respectively.

AB - Spermadhesins, 12,000-14,000 Mr mammalian proteins, include lectins involved in sperm-egg binding and display a single CUB domain architecture. We report the crystal structures of porcine seminal plasma PSP-I/PSP-II, a heterodimer of two glycosylated spermadhesins, and bovine aSFP at 2.4 Å and 1.9 Å resolution respectively.

UR - http://www.scopus.com/inward/record.url?scp=0031255268&partnerID=8YFLogxK

U2 - 10.1038/nsb1097-783

DO - 10.1038/nsb1097-783

M3 - Article

C2 - 9334740

AN - SCOPUS:0031255268

SN - 1072-8368

VL - 4

SP - 783

EP - 788

JO - Nature Structural Biology

JF - Nature Structural Biology

IS - 10

ER -

The crystal structures of two spermadhesins reveal the CUB domain fold

Abstract

Access to Document

Other files and links

Fingerprint

Cite this