TY - JOUR
T1 - The Cahn, Ingold and Prelog System
T2 - Eliminating ambiguity in the comparison of diastereomorphic and enantiomorphic ligands
AU - Mata, Paulina
AU - Lobo, Ana M.
PY - 2005/7/4
Y1 - 2005/7/4
N2 - The Cahn, Ingold and Prelog (CIP) system is an essential tool in organic chemistry nomenclature for the specification of stereogenic units. However, over the years, examples of molecules for which such specification was found impossible, ambiguous or inconsistent, have steadily accumulated. Herein, a simple methodology for the comparison of combinations of chiral units, namely to evaluate if two ligands are diastereomorphic, enantiomorphic or identical, is proposed, based on a reference descriptor not linked to a digraph node.
AB - The Cahn, Ingold and Prelog (CIP) system is an essential tool in organic chemistry nomenclature for the specification of stereogenic units. However, over the years, examples of molecules for which such specification was found impossible, ambiguous or inconsistent, have steadily accumulated. Herein, a simple methodology for the comparison of combinations of chiral units, namely to evaluate if two ligands are diastereomorphic, enantiomorphic or identical, is proposed, based on a reference descriptor not linked to a digraph node.
KW - cip-system
KW - specification
KW - revision
UR - http://www.scopus.com/inward/record.url?scp=22044458625&partnerID=8YFLogxK
U2 - 10.1016/j.tetasy.2005.05.037
DO - 10.1016/j.tetasy.2005.05.037
M3 - Article
SN - 0957-4166
VL - 16
SP - 2215
EP - 2223
JO - Tetrahedron-Asymmetry
JF - Tetrahedron-Asymmetry
IS - 13
ER -