The aza-wharton reaction: Syntheses of cyclic allylic amines and vicinal hydroxyamines from the respective acylaziridines

Saúl Silva, Paula Rodrigues, Isabel Bento, Christopher D. Maycock

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The Wharton reaction, initially described for acyl epoxides, has been studied using the structurally similar aziridines. By this reaction, a range of cyclic allylic amines and vicinal amino alcohols have been prepared stereoselectively and, in some cases, enantiomerically pure.

Original languageEnglish
Pages (from-to)3067-3074
Number of pages8
JournalJournal of Organic Chemistry
Volume80
Issue number6
DOIs
Publication statusPublished - 20 Mar 2015

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