Abstract
The Wharton reaction, initially described for acyl epoxides, has been studied using the structurally similar aziridines. By this reaction, a range of cyclic allylic amines and vicinal amino alcohols have been prepared stereoselectively and, in some cases, enantiomerically pure.
| Original language | English |
|---|---|
| Pages (from-to) | 3067-3074 |
| Number of pages | 8 |
| Journal | Journal of Organic Chemistry |
| Volume | 80 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 20 Mar 2015 |
Fingerprint Dive into the research topics of 'The aza-wharton reaction: Syntheses of cyclic allylic amines and vicinal hydroxyamines from the respective acylaziridines'. Together they form a unique fingerprint.
Cite this
Silva, S., Rodrigues, P., Bento, I., & Maycock, C. D. (2015). The aza-wharton reaction: Syntheses of cyclic allylic amines and vicinal hydroxyamines from the respective acylaziridines. Journal of Organic Chemistry, 80(6), 3067-3074. https://doi.org/10.1021/jo5029387