The quality of care provided to citizens by professionals and institutions depends on the quality and availability of information. Early commencement of treatment and medication, and the decisions on how to proceed, depend a lot on patients' data in the different modalities available. It is also important to notice that large pools of data help inform health and wellbeing parameters for the largest possible community. To make that possible it is necessary both to have the best hospital practices but also to get consent and collaboration from patients. In order to accomplish such a goal, it is necessary to use practices, which adhere to legal constraints and are transparent while handling data and also to transmit those practices and protocols to professionals and patients. The present document aims to provide a framework envisaging the seamless application of the clinical procedures, following legal guidance and making the process known, secure and trustworthy. It aims to contribute to clinical practice, and clinical research, thereby contributing to big data analysis by ensuring trust and best clinical data handling.