Lúpus eritematoso sistiémico e anemia.

Translated title of the contribution: Systemic lupus erythematosus and anaemia

S. Falcão, R. C. Barros, M Mateus, P. Nero, A. P Alves De Matos, José Bravo Pimentão, I. Ribeiro, André Weigert, Jaime Branco

Research output: Contribution to journalArticle

2 Citations (Scopus)
4 Downloads (Pure)

Abstract

The authors report the case of a 48-years-old Caucasian women, with a previous diagnosis of systemic lupus erythematosus characterized by asthenia, fever, skin rash, alopecia, Raynaud's phenomenon, arthritis, pericardial effusion, interstitial pulmonary involvement, diffuse proliferative glomerulonephritis with crescents and anemia. The presence of severe anemia refractory to high doses of glucocorticoids (1 mg/ /Kg/day), iron therapy and blood transfusions, associated with a low reticulocyte count determined the execution of a bone marrow aspiration, biopsy and immunophenotyping, which were compatible with the diagnosis of Myelodysplastic Syndrome. The treatment with erythropoietin (5.000U 3x/week) and cyclophosphamide pulses (1 gr/m(2) month) induced complete regression of morphologic bone marrow changes and anemia. The main causes of anemia in lupus patients are discussed.

Original languagePortuguese
Pages (from-to)73-79
Number of pages7
JournalActa reumatologica portuguesa
Volume32
Issue number1
Publication statusPublished - Jan 2007

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Systemic Lupus Erythematosus
Anemia
Bone Marrow
Refractory Anemia
Reticulocyte Count
Asthenia
Immunophenotyping
Raynaud Disease
Pericardial Effusion
Myelodysplastic Syndromes
Alopecia
Needle Biopsy
Erythropoietin
Glomerulonephritis
Exanthema
Blood Transfusion
Cyclophosphamide
Glucocorticoids
Arthritis
Fever

Keywords

  • systemic lupus erythematosus
  • myelodysplastic syndrome
  • anemia

Cite this

Falcão, S., Barros, R. C., Mateus, M., Nero, P., De Matos, A. P. A., Pimentão, J. B., ... Branco, J. (2007). Lúpus eritematoso sistiémico e anemia. Acta reumatologica portuguesa, 32(1), 73-79.
Falcão, S. ; Barros, R. C. ; Mateus, M ; Nero, P. ; De Matos, A. P Alves ; Pimentão, José Bravo ; Ribeiro, I. ; Weigert, André ; Branco, Jaime. / Lúpus eritematoso sistiémico e anemia. In: Acta reumatologica portuguesa. 2007 ; Vol. 32, No. 1. pp. 73-79.
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Falcão, S, Barros, RC, Mateus, M, Nero, P, De Matos, APA, Pimentão, JB, Ribeiro, I, Weigert, A & Branco, J 2007, 'Lúpus eritematoso sistiémico e anemia.', Acta reumatologica portuguesa, vol. 32, no. 1, pp. 73-79.

Lúpus eritematoso sistiémico e anemia. / Falcão, S.; Barros, R. C.; Mateus, M; Nero, P.; De Matos, A. P Alves; Pimentão, José Bravo; Ribeiro, I.; Weigert, André; Branco, Jaime.

In: Acta reumatologica portuguesa, Vol. 32, No. 1, 01.2007, p. 73-79.

Research output: Contribution to journalArticle

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AU - Barros, R. C.

AU - Mateus, M

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AU - Pimentão, José Bravo

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Falcão S, Barros RC, Mateus M, Nero P, De Matos APA, Pimentão JB et al. Lúpus eritematoso sistiémico e anemia. Acta reumatologica portuguesa. 2007 Jan;32(1):73-79.