Synthetic applications of N-Aryl-O-acyl hydroxymic acids. A convenient route to 3-substituted N-Benzoyl oxindoles

Paulo S. Almeida, Sundaresan Prabhakar, Ana M. Lobo, M. João Marcelo-Curlo

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

The enol silylethers of N-acyloxybenzanilides undergo smooth rearrangement to afford o-amino-benzoyl-phenylacetic acids and thence to oxindoles by dehydration.

Original languageEnglish
Pages (from-to)2671-2674
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number23
DOIs
Publication statusPublished - 3 Jun 1991

Keywords

  • 3,3-rearrangement
  • cyclisation
  • O-acyl hydroxamic acid
  • O-silylether
  • Oxindole

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