@article{3d1305e41b4f4f8aa9b53b2c839c39dd,
title = "Synthesis of Bis(3-indolyl)methanes Mediated by Potassium tert-Butoxide",
abstract = "The indole moiety is an important N-heterocycle found in natural products, and a key structural component of many value-added chemicals including pharmaceuticals. In particular, bis(3-indolyl)methanes (BIMs) are an important subgroup of indoles, composed of two indole units. Herein, we report the development of a simple method to access BIMs derivatives in yields of up to 77 % by exploiting a tBuOK-mediated coupling reaction of indoles and benzyl alcohols.",
keywords = "bis(indolyl)methanes, indole, tBuOK, radicals, benzylalcohols",
author = "Santos, {A. Sofia} and Ferro, {Rita D.} and Nuno Viduedo and Maia, {Lu{\'i}sa B.} and Silva, {Artur M. S.} and Marques, {M. Manuel B.}",
note = "info:eu-repo/grantAgreement/FCT/OE/PD%2FBD%2F142876%2F2018/PT# info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50006%2F2020/PT# info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F50006%2F2020/PT# info:eu-repo/grantAgreement/FCT/CEEC IND 2017/CEECIND%2F03810%2F2017%2FCP1462%2FCT0017/PT# The National NMR Facility is supported by FCT, ROTEIRO/0031/2013-PINFRA/22161/2016, co-financed by FEDER through COMPETE2020, POCI, and PORLandFCT through PIDDAC) and CERMAX(022162). ",
year = "2023",
month = jan,
doi = "10.1002/open.202200265",
language = "English",
volume = "12",
journal = "ChemistryOpen",
issn = "2191-1363",
publisher = "Wiley-VCH Verlag | Wiley Open Access",
number = "1",
}