Synthesis of a 3-hydroxyl-free N-acetyl glucosamine disaccharide

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Abstract

A simple and alternative route to a versatile N-acetyl glucosamine disaccharide building block was developed, possessing a free 3-hydroxyl group. In this strategy, the 2,2,2-trichloro-ethoxy carbonyl (Troc) group was used as an amino-and 3-hydroxyl-protecting group.

Original languageEnglish
Pages (from-to)90-100
Number of pages11
JournalArkivoc
Volume2012
Issue number6
DOIs
Publication statusPublished - 5 Feb 2012

Keywords

  • Glucosamine
  • Glycosylation
  • N-acetyl glucosamine
  • Trichloro-ethoxycarbonyl group

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