Synthesis of 2,4,6-tri-substituted-1,3,5-triazines

Carlos M. Afonso, N. M. T. Lourenço, Andreia Rosatella

Research output: Contribution to journalArticle

64 Citations (Scopus)


Several specific synthetic protocols were developed for the preparation from cyanuric chloride of a range of symmetric and non-symmetric, di- and tri-substituted 1,3,5-triazines containing alkyl, aromatic, hindered, chiral and achiral hydroxyalkyl, ester and imidazole groups via sequential nucleophilic substitution of the C-Cl bond by C-O, C-N and C-S bonds.
Original languageEnglish
Pages (from-to)81-102
Number of pages22
Issue number1
Publication statusPublished - 1 Jan 2006


  • Melamine derivatives
  • S-triazine
  • 1,3,5-triazine
  • Cyanuric chloride

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