Synthesis, characterization and metal ion detection of novel fluoroionophores based on heterocyclic substituted alanines

S.P.G. Costa, E. Oliveira, C. Lodeiro, M.M.M. Raposo

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

The synthesis of new fluorescent probes containing the thiophene and benzoxazole moieties combined with an alanine residue is described. The resulting highly fluorescent heterocyclic alanine derivatives respond via a quenching effect, with paramagnetic Cu(II) and Ni(II) metal ions and with diamagnetic Hg(II), as shown by the absorption and steady-state fluorescence spectroscopy studies. The formation of mononuclear or dinuclear metal complexes was postulated based on the presence of the free carboxylic acid as binding site and also with the interaction with the donor atoms in the chromophore. Interaction with other important biological metal ions such as Zn(II), Ca(II) and Na(I) was also explored. © 2007 by MDPI.
Original languageEnglish
Pages (from-to)2096-2114
Number of pages19
JournalSensors
Volume7
Issue number10
DOIs
Publication statusPublished - 2007

Keywords

  • Amino acids
  • Benzoxazole
  • Fluorescence
  • Fluorescent probes
  • Thiophene
  • Alanine derivatives
  • Alanine residues
  • Dinuclear metal complex
  • Metal ion detection
  • New fluorescent probes
  • Steady-state fluorescence
  • Chromophores
  • Fluorescence spectroscopy
  • Metal complexes
  • Metal ions
  • Synthesis (chemical)
  • Zinc compounds

Fingerprint Dive into the research topics of 'Synthesis, characterization and metal ion detection of novel fluoroionophores based on heterocyclic substituted alanines'. Together they form a unique fingerprint.

Cite this