Synthesis and Characterization of Iron Containing Bioactive Glass for Implants

I. Hammami; S. R. Gavinho; A. S. Pádua; M. P. F. Graça; J. C. Silva

doi:10.1109/EHB55594.2022.9991451

Synthesis and Characterization of Iron Containing Bioactive Glass for Implants

I. Hammami, S. R. Gavinho, A. S. Pádua, M. P. F. Graça, J. C. Silva

CENIMAT-i3N - Centro de Investigação de Materiais (Lab. Associado I3N)

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

6 Citations (Scopus)

Abstract

This work aims to develop a biomaterial for implants with superior antibacterial function, better angiogenesis and rapid osteointegration. For this purpose, 45S5 bioglasses modified by adding different amount of iron oxide (Fe3O4), from 0 to 8 mol%, were prepared by melt-quenching technique. The structure of the prepared glasses studied by XRD and FTIR showed that the insertion of Fe3O4 do not induce significant changes and thus not affect the beneficial characteristics of the bioglass. Since the electrically polarized bioactive glass and ceramics have been demonstrated to enhance their osteoconductivities, the AC and DC electrical conductivity have been investigated using impedance spectroscopy in the frequency range from 10² to 10⁶ Hz and over the temperature range, 200-400 K. The effects of iron loading on the charge transport mobility were studied. The biocompatibility of the glasses was evaluated in vitro by cell-biomaterial interaction test which show that the glasses are viable for biomedical applications.

Original language	English
Title of host publication	2022 10th E-Health and Bioengineering Conference, EHB 2022
Place of Publication	New Jersey
Publisher	Institute of Electrical and Electronics Engineers (IEEE)
Number of pages	4
ISBN (Electronic)	978-1-6654-8557-9
ISBN (Print)	978-1-6654-8558-6
DOIs	https://doi.org/10.1109/EHB55594.2022.9991451
Publication status	Published - 2022
Event	10th E-Health and Bioengineering Conference, EHB 2022 - Virtual, Online, Romania Duration: 17 Nov 2022 → 18 Nov 2022

Publication series

Name	2022 10th E-Health and Bioengineering Conference, EHB 2022
Publisher	IEEE
ISSN (Print)	2575-5137
ISSN (Electronic)	2575-5145

Conference

Conference	10th E-Health and Bioengineering Conference, EHB 2022
Country/Territory	Romania
City	Virtual, Online
Period	17/11/22 → 18/11/22

Keywords

Bioactive glass
Biomaterial
Cytotoxicity
Electrical properties

Access to Document

10.1109/EHB55594.2022.9991451

Cite this

Hammami, I., Gavinho, S. R., Pádua, A. S., Graça, M. P. F., & Silva, J. C. (2022). Synthesis and Characterization of Iron Containing Bioactive Glass for Implants. In 2022 10th E-Health and Bioengineering Conference, EHB 2022 (2022 10th E-Health and Bioengineering Conference, EHB 2022). Institute of Electrical and Electronics Engineers (IEEE). https://doi.org/10.1109/EHB55594.2022.9991451

@inproceedings{33a996610c7b4f48a52e380f8222fd42,

title = "Synthesis and Characterization of Iron Containing Bioactive Glass for Implants",

abstract = "This work aims to develop a biomaterial for implants with superior antibacterial function, better angiogenesis and rapid osteointegration. For this purpose, 45S5 bioglasses modified by adding different amount of iron oxide (Fe3O4), from 0 to 8 mol%, were prepared by melt-quenching technique. The structure of the prepared glasses studied by XRD and FTIR showed that the insertion of Fe3O4 do not induce significant changes and thus not affect the beneficial characteristics of the bioglass. Since the electrically polarized bioactive glass and ceramics have been demonstrated to enhance their osteoconductivities, the AC and DC electrical conductivity have been investigated using impedance spectroscopy in the frequency range from 102 to 106 Hz and over the temperature range, 200-400 K. The effects of iron loading on the charge transport mobility were studied. The biocompatibility of the glasses was evaluated in vitro by cell-biomaterial interaction test which show that the glasses are viable for biomedical applications.",

keywords = "Bioactive glass, Biomaterial, Cytotoxicity, Electrical properties",

author = "I. Hammami and Gavinho, {S. R.} and P{\'a}dua, {A. S.} and Gra{\c c}a, {M. P. F.} and Silva, {J. C.}",

note = "Funding Information: info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04378%2F2020/PT# info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04378%2F2020/PT# info:eu-repo/grantAgreement/FCT/POR_CENTRO/SFRH%2FBD%2F148233%2F2019/PT# ACKNOWLEDGMENT This work was supported by FEDER funds through the COMPETE 2020 Program and National Funds through FCT— Portuguese Foundation for Science and Technology under the project LISBOA-01-0247-FEDER-039985/POCI-01-0247-FEDER-039985 and UID/CTM/50025/2020, and Associate Laboratory i4HB (LA/P/0140/2020). Publisher Copyright: {\textcopyright} 2022 IEEE.; 10th E-Health and Bioengineering Conference, EHB 2022 ; Conference date: 17-11-2022 Through 18-11-2022",

year = "2022",

doi = "10.1109/EHB55594.2022.9991451",

language = "English",

isbn = "978-1-6654-8558-6",

series = "2022 10th E-Health and Bioengineering Conference, EHB 2022",

publisher = "Institute of Electrical and Electronics Engineers (IEEE)",

booktitle = "2022 10th E-Health and Bioengineering Conference, EHB 2022",

address = "United States",

}

Hammami, I, Gavinho, SR, Pádua, AS , Graça, MPF & Silva, JC 2022, Synthesis and Characterization of Iron Containing Bioactive Glass for Implants. in 2022 10th E-Health and Bioengineering Conference, EHB 2022. 2022 10th E-Health and Bioengineering Conference, EHB 2022, Institute of Electrical and Electronics Engineers (IEEE), New Jersey, 10th E-Health and Bioengineering Conference, EHB 2022, Virtual, Online, Romania, 17/11/22. https://doi.org/10.1109/EHB55594.2022.9991451

Synthesis and Characterization of Iron Containing Bioactive Glass for Implants. / Hammami, I.; Gavinho, S. R.; Pádua, A. S. et al.
2022 10th E-Health and Bioengineering Conference, EHB 2022. New Jersey: Institute of Electrical and Electronics Engineers (IEEE), 2022. (2022 10th E-Health and Bioengineering Conference, EHB 2022).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Synthesis and Characterization of Iron Containing Bioactive Glass for Implants

AU - Hammami, I.

AU - Gavinho, S. R.

AU - Pádua, A. S.

AU - Graça, M. P. F.

AU - Silva, J. C.

N1 - Funding Information: info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDP%2F04378%2F2020/PT# info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F04378%2F2020/PT# info:eu-repo/grantAgreement/FCT/POR_CENTRO/SFRH%2FBD%2F148233%2F2019/PT# ACKNOWLEDGMENT This work was supported by FEDER funds through the COMPETE 2020 Program and National Funds through FCT— Portuguese Foundation for Science and Technology under the project LISBOA-01-0247-FEDER-039985/POCI-01-0247-FEDER-039985 and UID/CTM/50025/2020, and Associate Laboratory i4HB (LA/P/0140/2020). Publisher Copyright: © 2022 IEEE.

PY - 2022

Y1 - 2022

N2 - This work aims to develop a biomaterial for implants with superior antibacterial function, better angiogenesis and rapid osteointegration. For this purpose, 45S5 bioglasses modified by adding different amount of iron oxide (Fe3O4), from 0 to 8 mol%, were prepared by melt-quenching technique. The structure of the prepared glasses studied by XRD and FTIR showed that the insertion of Fe3O4 do not induce significant changes and thus not affect the beneficial characteristics of the bioglass. Since the electrically polarized bioactive glass and ceramics have been demonstrated to enhance their osteoconductivities, the AC and DC electrical conductivity have been investigated using impedance spectroscopy in the frequency range from 102 to 106 Hz and over the temperature range, 200-400 K. The effects of iron loading on the charge transport mobility were studied. The biocompatibility of the glasses was evaluated in vitro by cell-biomaterial interaction test which show that the glasses are viable for biomedical applications.

AB - This work aims to develop a biomaterial for implants with superior antibacterial function, better angiogenesis and rapid osteointegration. For this purpose, 45S5 bioglasses modified by adding different amount of iron oxide (Fe3O4), from 0 to 8 mol%, were prepared by melt-quenching technique. The structure of the prepared glasses studied by XRD and FTIR showed that the insertion of Fe3O4 do not induce significant changes and thus not affect the beneficial characteristics of the bioglass. Since the electrically polarized bioactive glass and ceramics have been demonstrated to enhance their osteoconductivities, the AC and DC electrical conductivity have been investigated using impedance spectroscopy in the frequency range from 102 to 106 Hz and over the temperature range, 200-400 K. The effects of iron loading on the charge transport mobility were studied. The biocompatibility of the glasses was evaluated in vitro by cell-biomaterial interaction test which show that the glasses are viable for biomedical applications.

KW - Bioactive glass

KW - Biomaterial

KW - Cytotoxicity

KW - Electrical properties

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U2 - 10.1109/EHB55594.2022.9991451

DO - 10.1109/EHB55594.2022.9991451

M3 - Conference contribution

AN - SCOPUS:85146606125

SN - 978-1-6654-8558-6

T3 - 2022 10th E-Health and Bioengineering Conference, EHB 2022

BT - 2022 10th E-Health and Bioengineering Conference, EHB 2022

PB - Institute of Electrical and Electronics Engineers (IEEE)

CY - New Jersey

T2 - 10th E-Health and Bioengineering Conference, EHB 2022

Y2 - 17 November 2022 through 18 November 2022

ER -

Hammami I, Gavinho SR, Pádua AS , Graça MPF , Silva JC. Synthesis and Characterization of Iron Containing Bioactive Glass for Implants. In 2022 10th E-Health and Bioengineering Conference, EHB 2022. New Jersey: Institute of Electrical and Electronics Engineers (IEEE). 2022. (2022 10th E-Health and Bioengineering Conference, EHB 2022). doi: 10.1109/EHB55594.2022.9991451

Synthesis and Characterization of Iron Containing Bioactive Glass for Implants

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Keywords

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