TY - JOUR
T1 - Suicidality in primary care patients who present with sadness and anhedonia
T2 - A prospective European study
AU - Moreno-Küstner, Berta
AU - Jones, Rebeca
AU - Švab, Igor
AU - Maaroos, Heidi
AU - Xavier, Miguel
AU - Geerlings, Mirjam
AU - Torres-González, Francisco
AU - Nazareth, Irwin
AU - Motrico-Martínez, Emma
AU - Montón-Franco, Carmen
AU - Gil-de-Gómez, María José
AU - Sánchez-Celaya, Marta
AU - Díaz-Barreiros, Miguel Ángel
AU - Vicens-Caldentey, Catalina
AU - King, Michael
PY - 2016/4/6
Y1 - 2016/4/6
N2 - Background: Sadness and anhedonia (loss of interest in activities) are central symptoms of major depression. However, not all people with these symptoms meet diagnostic criteria for major depression. We aimed to assess the importance of suicidality in the outcomes for primary care patients who present with sadness and anhedonia. Method: Cohort study of 2,599 unselected primary care attenders in six European countries followed up at 6 and 12 months. Results: 1) In patients with sadness and/or anhedonia who were not depressed at entry to the study, suicide plans (OR = 3.05; 95 % CI = 1.50-6.24; p = 0.0022) and suicide attempts (OR = 9.08; 95 % CI = 2.57-32.03; p = 0.0006) were significant predictors of developing new onset depression at 6 or 12 months. 2) In patients with sadness and/or anhedonia who met CIDI criteria for major depression at entry, suicidal ideation (OR = 2.93; 95 % CI = 1.70-5.07; p = 0.0001), suicide plans (OR = 3.70; 95 % CI = 2.08-6.57; p < 0.0001), and suicide attempts (OR = 3.33; 95 % CI = 1.47-7.54; p = 0.0040) were significant predictors of persistent depression at 6 or 12 months. Conclusions: Three questions on suicidality could help primary care professionals to assess such patients more closely without necessarily establishing whether they meet criteria for major depression.
AB - Background: Sadness and anhedonia (loss of interest in activities) are central symptoms of major depression. However, not all people with these symptoms meet diagnostic criteria for major depression. We aimed to assess the importance of suicidality in the outcomes for primary care patients who present with sadness and anhedonia. Method: Cohort study of 2,599 unselected primary care attenders in six European countries followed up at 6 and 12 months. Results: 1) In patients with sadness and/or anhedonia who were not depressed at entry to the study, suicide plans (OR = 3.05; 95 % CI = 1.50-6.24; p = 0.0022) and suicide attempts (OR = 9.08; 95 % CI = 2.57-32.03; p = 0.0006) were significant predictors of developing new onset depression at 6 or 12 months. 2) In patients with sadness and/or anhedonia who met CIDI criteria for major depression at entry, suicidal ideation (OR = 2.93; 95 % CI = 1.70-5.07; p = 0.0001), suicide plans (OR = 3.70; 95 % CI = 2.08-6.57; p < 0.0001), and suicide attempts (OR = 3.33; 95 % CI = 1.47-7.54; p = 0.0040) were significant predictors of persistent depression at 6 or 12 months. Conclusions: Three questions on suicidality could help primary care professionals to assess such patients more closely without necessarily establishing whether they meet criteria for major depression.
KW - Anhedonia
KW - Cohort
KW - Depression
KW - Primary care
KW - Risk
KW - Suicidality
UR - http://www.scopus.com/inward/record.url?scp=84963577265&partnerID=8YFLogxK
U2 - 10.1186/s12888-016-0775-z
DO - 10.1186/s12888-016-0775-z
M3 - Article
C2 - 27053286
AN - SCOPUS:84963577265
SN - 1471-244X
VL - 16
JO - BMC Psychiatry
JF - BMC Psychiatry
IS - 1
M1 - 94
ER -