Structural-functional evaluation of ionic liquid libraries for the design of co-solvents in lipase-catalysed reactions

João V. Rodrigues; Diana Ruivo; Ana Rodríguez; Francisco J. Deive; José M S S Esperança; Isabel Maria Marrucho Ferreira; Claudio Emanuel Gomes; Luis Paulo da Silva Nieto Marques Rebelo

doi:10.1039/c4gc01329h

Structural-functional evaluation of ionic liquid libraries for the design of co-solvents in lipase-catalysed reactions

João V. Rodrigues, Diana Ruivo, Ana Rodríguez, Francisco J. Deive, José M S S Esperança, Isabel Maria Marrucho Ferreira, Claudio Emanuel Gomes, Luis Paulo da Silva Nieto Marques Rebelo

Instituto de Tecnologia Química e Biológica António Xavier (ITQB)

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

Using ionic liquids as co-solvents may improve reaction media in enzyme-based biotechnological processes. To establish new conditions, large libraries need to be screened for bio-compatibility and protein stabilisation. Using a lipase model, we herein describe a combination of methods leading to an expedited evaluation of 61 different solvent compositions. This journal is

Original language	English
Pages (from-to)	4520-4523
Number of pages	4
Journal	Green Chemistry
Volume	16
Issue number	10
DOIs	https://doi.org/10.1039/c4gc01329h
Publication status	Published - 1 Oct 2014

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AU - Rodrigues, João V.

AU - Ruivo, Diana

AU - Rodríguez, Ana

AU - Deive, Francisco J.

AU - Esperança, José M S S

AU - Marrucho Ferreira, Isabel Maria

AU - Gomes, Claudio Emanuel

AU - Rebelo, Luis Paulo da Silva Nieto Marques

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AB - Using ionic liquids as co-solvents may improve reaction media in enzyme-based biotechnological processes. To establish new conditions, large libraries need to be screened for bio-compatibility and protein stabilisation. Using a lipase model, we herein describe a combination of methods leading to an expedited evaluation of 61 different solvent compositions. This journal is

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Structural-functional evaluation of ionic liquid libraries for the design of co-solvents in lipase-catalysed reactions

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