Abstract
INTRODUCTION: Tolosa-Hunt syndrome (THS) is one of the most common 'benign' causes of painful ophthalmoplegia. Diagnosis is based on clinical and imaging findings and the exclusion of other causes because there is no specific biomarker for the syndrome. Eales disease, an idiopathic inflammatory venous disease that primarily affects the eye, can also affect the central (as stroke or myelitis) and peripheral nervous system.
CASE REPORT: We report the case of a 32-year-old woman with a subacute left ophthalmoplegia and evidence of a gadolinium-enhanced lesion suggesting an inflammatory granuloma that resolved within 48 hours after treatment with steroids. A diagnosis of THS was considered at this time. On a follow-up ophthalmological examination, a diagnosis of Eales disease with involvement of the left eye was made. The patient was treated successfully.
CONCLUSION: Eales disease could be a cause of painful ophthalmoplegia and may mimic THS. Long-term follow-up of patients diagnosed with THS may be necessary to exclude other diagnoses.
| Original language | English |
|---|---|
| Pages (from-to) | 191-194 |
| Number of pages | 4 |
| Journal | Cephalalgia |
| Volume | 37 |
| Issue number | 2 |
| Early online date | 11 Jul 2016 |
| DOIs | |
| Publication status | Published - Feb 2017 |
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Keywords
- Eales disease
- Tolosa–Hunt syndrome
- painful ophthalmoplegia
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Steroid-responsive painful ophthalmoplegia : Tolosa-Hunt syndrome, Eales disease, or both? / Mendonça, MD; Guedes, Marta; Matias, Gonçalo; Costa, João; Viana-Baptista, M .
In: Cephalalgia, Vol. 37, No. 2, 02.2017, p. 191-194.Research output: Contribution to journal › Editorial
TY - JOUR
T1 - Steroid-responsive painful ophthalmoplegia
T2 - Tolosa-Hunt syndrome, Eales disease, or both?
AU - Mendonça, MD
AU - Guedes, Marta
AU - Matias, Gonçalo
AU - Costa, João
AU - Viana-Baptista, M
N1 - © International Headache Society 2016.
PY - 2017/2
Y1 - 2017/2
N2 - INTRODUCTION: Tolosa-Hunt syndrome (THS) is one of the most common 'benign' causes of painful ophthalmoplegia. Diagnosis is based on clinical and imaging findings and the exclusion of other causes because there is no specific biomarker for the syndrome. Eales disease, an idiopathic inflammatory venous disease that primarily affects the eye, can also affect the central (as stroke or myelitis) and peripheral nervous system.CASE REPORT: We report the case of a 32-year-old woman with a subacute left ophthalmoplegia and evidence of a gadolinium-enhanced lesion suggesting an inflammatory granuloma that resolved within 48 hours after treatment with steroids. A diagnosis of THS was considered at this time. On a follow-up ophthalmological examination, a diagnosis of Eales disease with involvement of the left eye was made. The patient was treated successfully.CONCLUSION: Eales disease could be a cause of painful ophthalmoplegia and may mimic THS. Long-term follow-up of patients diagnosed with THS may be necessary to exclude other diagnoses.
AB - INTRODUCTION: Tolosa-Hunt syndrome (THS) is one of the most common 'benign' causes of painful ophthalmoplegia. Diagnosis is based on clinical and imaging findings and the exclusion of other causes because there is no specific biomarker for the syndrome. Eales disease, an idiopathic inflammatory venous disease that primarily affects the eye, can also affect the central (as stroke or myelitis) and peripheral nervous system.CASE REPORT: We report the case of a 32-year-old woman with a subacute left ophthalmoplegia and evidence of a gadolinium-enhanced lesion suggesting an inflammatory granuloma that resolved within 48 hours after treatment with steroids. A diagnosis of THS was considered at this time. On a follow-up ophthalmological examination, a diagnosis of Eales disease with involvement of the left eye was made. The patient was treated successfully.CONCLUSION: Eales disease could be a cause of painful ophthalmoplegia and may mimic THS. Long-term follow-up of patients diagnosed with THS may be necessary to exclude other diagnoses.
KW - Eales disease
KW - Tolosa–Hunt syndrome
KW - painful ophthalmoplegia
U2 - 10.1177/0333102416631282
DO - 10.1177/0333102416631282
M3 - Editorial
VL - 37
SP - 191
EP - 194
JO - Cephalalgia
JF - Cephalalgia
SN - 0333-1024
IS - 2
ER -