Spectroscopic studies of ketones as a marker for patients with diabetes

F. Ferreira da Silva; M. Nobre; A Fernandes; R. Antunes; D. Almeida; G. Garcia; N. J. Mason; P. Limao-Vieira

doi:10.1088/1742-659/101/1/012011

Spectroscopic studies of ketones as a marker for patients with diabetes

F. Ferreira da Silva, M. Nobre, A Fernandes, R. Antunes, D. Almeida, G. Garcia, N. J. Mason, P. Limao-Vieira

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

6 Citations (Scopus)

Abstract

Acetone in human breath has been established as a biomarker for diabetes. The application of UV spectroscopy for the study of biomedical compounds has been developed over recent years but is often limited by the lack of absolute data for calibration of the instrumentation. By measuring high resolution absolute VUV photoabsorption cross sections of acetone, we are able to provide calibration values at several wavelengths with special attention to 4.661 eV (266 nm). Results are compared with recent published data [C Wang, A Mbi, Meas. Sci. Technol., 2007, 18, 2731-2741]. The acetone spectrum is here revisited from a recent contribution [Nobre M, et al, Phys Chem Chem Phys, 2008 (in press)] where the absolute cross sectional values are obtained in the 3.7 - 10.8 eV energy region. Future medical units working in close link with synchrotron radiation facilities can make use of the VUV spectra wavelength region to trace acetone in diabetic patients.

Original language	English
Title of host publication	Radiation Damage in Biomelecular Systems
Editors	KG McGuigan
Volume	101
DOIs	https://doi.org/10.1088/1742-659/101/1/012011
Publication status	Published - 1 Feb 2008

Publication series

Name	Journal of Physics Conference Series

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da Silva, F. F., Nobre, M., Fernandes, A., Antunes, R., Almeida, D., Garcia, G., ... Limao-Vieira, P. (2008). Spectroscopic studies of ketones as a marker for patients with diabetes. In KG. McGuigan (Ed.), Radiation Damage in Biomelecular Systems (Vol. 101). (Journal of Physics Conference Series). https://doi.org/10.1088/1742-659/101/1/012011

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abstract = "Acetone in human breath has been established as a biomarker for diabetes. The application of UV spectroscopy for the study of biomedical compounds has been developed over recent years but is often limited by the lack of absolute data for calibration of the instrumentation. By measuring high resolution absolute VUV photoabsorption cross sections of acetone, we are able to provide calibration values at several wavelengths with special attention to 4.661 eV (266 nm). Results are compared with recent published data [C Wang, A Mbi, Meas. Sci. Technol., 2007, 18, 2731-2741]. The acetone spectrum is here revisited from a recent contribution [Nobre M, et al, Phys Chem Chem Phys, 2008 (in press)] where the absolute cross sectional values are obtained in the 3.7 - 10.8 eV energy region. Future medical units working in close link with synchrotron radiation facilities can make use of the VUV spectra wavelength region to trace acetone in diabetic patients.",

author = "{da Silva}, {F. Ferreira} and M. Nobre and A Fernandes and R. Antunes and D. Almeida and G. Garcia and Mason, {N. J.} and P. Limao-Vieira",

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Spectroscopic studies of ketones as a marker for patients with diabetes. / da Silva, F. Ferreira; Nobre, M.; Fernandes, A; Antunes, R.; Almeida, D.; Garcia, G.; Mason, N. J.; Limao-Vieira, P.

Radiation Damage in Biomelecular Systems. ed. / KG McGuigan. Vol. 101 2008. (Journal of Physics Conference Series).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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