The present invention refers to an acceleration process for macromolecular fragmentation in liquid medium, in gel or in a solid support, by means of joint application of enzymes and ultrasounds, as well as isotopes. The macromolecules, in any of these liquids, are mixed with enzymes and inserted in a recipient (2) and exposed to an ultrasonic radiation field (1). The combined effect of the enzymes and of the ultrasounds allows accomplishing, in time ranges between 10 s and 600 s, the fragmentation of macromolecules or whole proteomes, with the correspondent formation of their constituent lower molecular units.
|IPC||C12Q 1/ 00 A I|
|Publication status||Published - 16 Apr 2008|