Selective acceleration of frangmentation through joint application of enzymes and ultrasound

J.l Capelo Martinez; Jesus Vazquez Cobos; Daniel Lopez Ferrer; Isabel Moura

Selective acceleration of frangmentation through joint application of enzymes and ultrasound

J.l Capelo Martinez (Inventor), Jesus Vazquez Cobos (Inventor), Daniel Lopez Ferrer (Inventor), Isabel Moura (Inventor)

Research output: Patent › Regional/Other National Application

Abstract

The present invention refers to an acceleration process for macromolecular fragmentation in liquid medium, in gel or in a solid support, by means of joint application of enzymes and ultrasounds, as well as isotopes. The macromolecules, in any of these liquids, are mixed with enzymes and inserted in a recipient (2) and exposed to an ultrasonic radiation field (1). The combined effect of the enzymes and of the ultrasounds allows accomplishing, in time ranges between 10 s and 600 s, the fragmentation of macromolecules or whole proteomes, with the correspondent formation of their constituent lower molecular units.

Original language	English
Patent number	EP1910551
IPC	C12Q 1/ 00 A I
Priority date	7/07/06
Filing date	7/07/06
Publication status	Published - 16 Apr 2008

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title = "Selective acceleration of frangmentation through joint application of enzymes and ultrasound",

abstract = "The present invention refers to an acceleration process for macromolecular fragmentation in liquid medium, in gel or in a solid support, by means of joint application of enzymes and ultrasounds, as well as isotopes. The macromolecules, in any of these liquids, are mixed with enzymes and inserted in a recipient (2) and exposed to an ultrasonic radiation field (1). The combined effect of the enzymes and of the ultrasounds allows accomplishing, in time ranges between 10 s and 600 s, the fragmentation of macromolecules or whole proteomes, with the correspondent formation of their constituent lower molecular units.",

author = "{Capelo Martinez}, J.l and {Vazquez Cobos}, Jesus and {Lopez Ferrer}, Daniel and Isabel Moura",

year = "2008",

month = apr,

day = "16",

language = "English",

type = "Patent",

note = "EP1910551; C12Q 1/ 00 A I",

}

TY - PAT

T1 - Selective acceleration of frangmentation through joint application of enzymes and ultrasound

AU - Capelo Martinez, J.l

AU - Vazquez Cobos, Jesus

AU - Lopez Ferrer, Daniel

AU - Moura, Isabel

PY - 2008/4/16

Y1 - 2008/4/16

N2 - The present invention refers to an acceleration process for macromolecular fragmentation in liquid medium, in gel or in a solid support, by means of joint application of enzymes and ultrasounds, as well as isotopes. The macromolecules, in any of these liquids, are mixed with enzymes and inserted in a recipient (2) and exposed to an ultrasonic radiation field (1). The combined effect of the enzymes and of the ultrasounds allows accomplishing, in time ranges between 10 s and 600 s, the fragmentation of macromolecules or whole proteomes, with the correspondent formation of their constituent lower molecular units.

AB - The present invention refers to an acceleration process for macromolecular fragmentation in liquid medium, in gel or in a solid support, by means of joint application of enzymes and ultrasounds, as well as isotopes. The macromolecules, in any of these liquids, are mixed with enzymes and inserted in a recipient (2) and exposed to an ultrasonic radiation field (1). The combined effect of the enzymes and of the ultrasounds allows accomplishing, in time ranges between 10 s and 600 s, the fragmentation of macromolecules or whole proteomes, with the correspondent formation of their constituent lower molecular units.

M3 - Regional/Other National Application

M1 - EP1910551

Y2 - 2006/07/07

ER -

Selective acceleration of frangmentation through joint application of enzymes and ultrasound

Abstract

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