Selective acceleration of fragmentation through joint application of enzymes and ultrasound

Martinez Jose Luis Capelo (Inventor), Cobos Jesus Vazquez (Inventor), Daniel Ferrer Lopez (Inventor), Isabel Moura (Inventor)

Research output: PatentRegional/Other National Application

Abstract

The present invention refers to an acceleration process for macromolecular fragmentation in liquid medium, in gel or in a solid support, by means of joint application of enzymes and ultrasounds, as well as isotopes. The macromolecules, in any of these liquids, are mixed with enzymes and inserted in a recipient (2) and exposed to an ultrasonic radiation field (1). The combined effect of the enzymes and of the ultrasounds allows accomplishing, in time ranges between 10 s and 600 s, the fragmentation of macromolecules or whole proteontes, with the correspondent formation of their constituent lower molecular units.

Original languageEnglish
Patent numberUS2009246813
IPC C12Q1/37, C12Q1/40
Priority date7/07/05
Filing date7/07/06
Publication statusPublished - 1 Oct 2009

Fingerprint

Dive into the research topics of 'Selective acceleration of fragmentation through joint application of enzymes and ultrasound'. Together they form a unique fingerprint.

Cite this