Abstract
The present invention refers to an acceleration process for macromolecular fragmentation in liquid medium, in gel or in a solid support, by means of joint application of enzymes and ultrasounds, as well as isotopes. The macromolecules, in any of these liquids, are mixed with enzymes and inserted in a recipient (2) and exposed to an ultrasonic radiation field (1). The combined effect of the enzymes and of the ultrasounds allows accomplishing, in time ranges between 10 s and 600 s, the fragmentation of macromolecules or whole proteontes, with the correspondent formation of their constituent lower molecular units.
Original language | English |
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Patent number | US2009246813 |
IPC | C12Q1/37, C12Q1/40 |
Priority date | 7/07/05 |
Filing date | 7/07/06 |
Publication status | Published - 1 Oct 2009 |