Secondary Epiretinal Membrane After Trabeculectomy

Luisa Mota-Vieira; Ana Cabugueira; Barbara Borges; Vanessa Carvalho; Manuel Noronha; Luis Abegao Pinto; Maria Reina; Marco Paulo Dutra Medeiros

doi:10.1097/IJG.0000000000000326

Secondary Epiretinal Membrane After Trabeculectomy

Luisa Mota-Vieira, Ana Cabugueira, Barbara Borges, Vanessa Carvalho, Manuel Noronha, Luis Abegao Pinto, Maria Reina, Marco Paulo Dutra Medeiros

NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

Purpose: To determine the frequency of epiretinal membranes (ERM) in eyes with primary open-angle glaucoma subjected to trabeculectomy.

Methods: We conducted a retrospective study on patients subjected to trabeculectomy with at least a 6-month follow-up. Ophthalmologic examination and spectral-domain optical coherence tomography (SD-OCT) were analyzed. Eyes with previous surgical or laser treatments or other pathologies (other than glaucoma and ERM) were excluded.

Results: A total of 50 eyes (40 patients) were included in this study. The mean follow-up time after surgery was 27.8 months. After surgery, 9 eyes (18%) had preretinal macular fibrosis and 19 eyes (38%) had cellophane macular reflex. Of the 16 eyes with a preoperative macular SD-OCT, 3 (18.8%) developed ERM and 4 (25%) progressed from cellophane macular reflex to preretinal macular fibrosis, after surgery. The ERM frequency did not differ significantly between eyes subjected to trabeculectomy with or without the use of antimetabolites (P = 0.08), or between eyes subjected to simple or combined surgery (phacotrabeculectomy) (P = 0.09).

Conclusion: Trabeculectomy may predispose one to the appearance and progression of ERM. Further studies are needed to clarify this intriguing relation.

Original language	English
Pages (from-to)	E576-E580
Number of pages	5
Journal	Journal of glaucoma
Volume	25
Issue number	6
DOIs	https://doi.org/10.1097/IJG.0000000000000326
Publication status	Published - Jun 2016

Keywords

5-fluoracyl
cellophane macular reflex
epiretinal membrane
mitomycin-C
preretinal macular fibrosis
phacotrabeculectomy
spectral domain-OCT
trabeculectomy
OPTICAL COHERENCE TOMOGRAPHY
BLUE MOUNTAINS EYE
RISK-FACTORS
PREVALENCE
ASSOCIATIONS
SURGERY
POPULATION
GLAUCOMA
FIBROSIS
CHINESE

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10.1097/IJG.0000000000000326

Cite this

@article{3ad72afb6a744dac917136d492e0ddfe,

title = "Secondary Epiretinal Membrane After Trabeculectomy",

abstract = "Purpose: To determine the frequency of epiretinal membranes (ERM) in eyes with primary open-angle glaucoma subjected to trabeculectomy.Methods: We conducted a retrospective study on patients subjected to trabeculectomy with at least a 6-month follow-up. Ophthalmologic examination and spectral-domain optical coherence tomography (SD-OCT) were analyzed. Eyes with previous surgical or laser treatments or other pathologies (other than glaucoma and ERM) were excluded.Results: A total of 50 eyes (40 patients) were included in this study. The mean follow-up time after surgery was 27.8 months. After surgery, 9 eyes (18%) had preretinal macular fibrosis and 19 eyes (38%) had cellophane macular reflex. Of the 16 eyes with a preoperative macular SD-OCT, 3 (18.8%) developed ERM and 4 (25%) progressed from cellophane macular reflex to preretinal macular fibrosis, after surgery. The ERM frequency did not differ significantly between eyes subjected to trabeculectomy with or without the use of antimetabolites (P = 0.08), or between eyes subjected to simple or combined surgery (phacotrabeculectomy) (P = 0.09).Conclusion: Trabeculectomy may predispose one to the appearance and progression of ERM. Further studies are needed to clarify this intriguing relation.",

keywords = "5-fluoracyl, cellophane macular reflex, epiretinal membrane, mitomycin-C, preretinal macular fibrosis, phacotrabeculectomy, spectral domain-OCT, trabeculectomy, OPTICAL COHERENCE TOMOGRAPHY, BLUE MOUNTAINS EYE, RISK-FACTORS, PREVALENCE, ASSOCIATIONS, SURGERY, POPULATION, GLAUCOMA, FIBROSIS, CHINESE",

author = "Luisa Mota-Vieira and Ana Cabugueira and Barbara Borges and Vanessa Carvalho and Manuel Noronha and Pinto, {Luis Abegao} and Maria Reina and Medeiros, {Marco Paulo Dutra}",

year = "2016",

month = jun,

doi = "10.1097/IJG.0000000000000326",

language = "English",

volume = "25",

pages = "E576--E580",

journal = "Journal of glaucoma",

issn = "1057-0829",

publisher = "Lippincott, Williams & Wilkins",

number = "6",

}

TY - JOUR

T1 - Secondary Epiretinal Membrane After Trabeculectomy

AU - Mota-Vieira, Luisa

AU - Cabugueira, Ana

AU - Borges, Barbara

AU - Carvalho, Vanessa

AU - Noronha, Manuel

AU - Pinto, Luis Abegao

AU - Reina, Maria

AU - Medeiros, Marco Paulo Dutra

PY - 2016/6

Y1 - 2016/6

N2 - Purpose: To determine the frequency of epiretinal membranes (ERM) in eyes with primary open-angle glaucoma subjected to trabeculectomy.Methods: We conducted a retrospective study on patients subjected to trabeculectomy with at least a 6-month follow-up. Ophthalmologic examination and spectral-domain optical coherence tomography (SD-OCT) were analyzed. Eyes with previous surgical or laser treatments or other pathologies (other than glaucoma and ERM) were excluded.Results: A total of 50 eyes (40 patients) were included in this study. The mean follow-up time after surgery was 27.8 months. After surgery, 9 eyes (18%) had preretinal macular fibrosis and 19 eyes (38%) had cellophane macular reflex. Of the 16 eyes with a preoperative macular SD-OCT, 3 (18.8%) developed ERM and 4 (25%) progressed from cellophane macular reflex to preretinal macular fibrosis, after surgery. The ERM frequency did not differ significantly between eyes subjected to trabeculectomy with or without the use of antimetabolites (P = 0.08), or between eyes subjected to simple or combined surgery (phacotrabeculectomy) (P = 0.09).Conclusion: Trabeculectomy may predispose one to the appearance and progression of ERM. Further studies are needed to clarify this intriguing relation.

AB - Purpose: To determine the frequency of epiretinal membranes (ERM) in eyes with primary open-angle glaucoma subjected to trabeculectomy.Methods: We conducted a retrospective study on patients subjected to trabeculectomy with at least a 6-month follow-up. Ophthalmologic examination and spectral-domain optical coherence tomography (SD-OCT) were analyzed. Eyes with previous surgical or laser treatments or other pathologies (other than glaucoma and ERM) were excluded.Results: A total of 50 eyes (40 patients) were included in this study. The mean follow-up time after surgery was 27.8 months. After surgery, 9 eyes (18%) had preretinal macular fibrosis and 19 eyes (38%) had cellophane macular reflex. Of the 16 eyes with a preoperative macular SD-OCT, 3 (18.8%) developed ERM and 4 (25%) progressed from cellophane macular reflex to preretinal macular fibrosis, after surgery. The ERM frequency did not differ significantly between eyes subjected to trabeculectomy with or without the use of antimetabolites (P = 0.08), or between eyes subjected to simple or combined surgery (phacotrabeculectomy) (P = 0.09).Conclusion: Trabeculectomy may predispose one to the appearance and progression of ERM. Further studies are needed to clarify this intriguing relation.

KW - 5-fluoracyl

KW - cellophane macular reflex

KW - epiretinal membrane

KW - mitomycin-C

KW - preretinal macular fibrosis

KW - phacotrabeculectomy

KW - spectral domain-OCT

KW - trabeculectomy

KW - OPTICAL COHERENCE TOMOGRAPHY

KW - BLUE MOUNTAINS EYE

KW - RISK-FACTORS

KW - PREVALENCE

KW - ASSOCIATIONS

KW - SURGERY

KW - POPULATION

KW - GLAUCOMA

KW - FIBROSIS

KW - CHINESE

U2 - 10.1097/IJG.0000000000000326

DO - 10.1097/IJG.0000000000000326

M3 - Article

C2 - 26398580

SN - 1057-0829

VL - 25

SP - E576-E580

JO - Journal of glaucoma

JF - Journal of glaucoma

IS - 6

ER -

Secondary Epiretinal Membrane After Trabeculectomy

Abstract

Keywords

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