Secondary Epiretinal Membrane After Trabeculectomy

Luisa Mota-Vieira, Ana Cabugueira, Barbara Borges, Vanessa Carvalho, Manuel Noronha, Luis Abegao Pinto, Maria Reina, Marco Paulo Dutra Medeiros

Research output: Contribution to journalArticle

Abstract

Purpose: To determine the frequency of epiretinal membranes (ERM) in eyes with primary open-angle glaucoma subjected to trabeculectomy.

Methods: We conducted a retrospective study on patients subjected to trabeculectomy with at least a 6-month follow-up. Ophthalmologic examination and spectral-domain optical coherence tomography (SD-OCT) were analyzed. Eyes with previous surgical or laser treatments or other pathologies (other than glaucoma and ERM) were excluded.

Results: A total of 50 eyes (40 patients) were included in this study. The mean follow-up time after surgery was 27.8 months. After surgery, 9 eyes (18%) had preretinal macular fibrosis and 19 eyes (38%) had cellophane macular reflex. Of the 16 eyes with a preoperative macular SD-OCT, 3 (18.8%) developed ERM and 4 (25%) progressed from cellophane macular reflex to preretinal macular fibrosis, after surgery. The ERM frequency did not differ significantly between eyes subjected to trabeculectomy with or without the use of antimetabolites (P = 0.08), or between eyes subjected to simple or combined surgery (phacotrabeculectomy) (P = 0.09).

Conclusion: Trabeculectomy may predispose one to the appearance and progression of ERM. Further studies are needed to clarify this intriguing relation.

Original languageEnglish
Pages (from-to)E576-E580
Number of pages5
JournalJournal of glaucoma
Volume25
Issue number6
DOIs
Publication statusPublished - Jun 2016

Keywords

  • 5-fluoracyl
  • cellophane macular reflex
  • epiretinal membrane
  • mitomycin-C
  • preretinal macular fibrosis
  • phacotrabeculectomy
  • spectral domain-OCT
  • trabeculectomy
  • OPTICAL COHERENCE TOMOGRAPHY
  • BLUE MOUNTAINS EYE
  • RISK-FACTORS
  • PREVALENCE
  • ASSOCIATIONS
  • SURGERY
  • POPULATION
  • GLAUCOMA
  • FIBROSIS
  • CHINESE

Cite this

Mota-Vieira, L., Cabugueira, A., Borges, B., Carvalho, V., Noronha, M., Pinto, L. A., ... Medeiros, M. P. D. (2016). Secondary Epiretinal Membrane After Trabeculectomy. Journal of glaucoma, 25(6), E576-E580. https://doi.org/10.1097/IJG.0000000000000326