Sample treatment for protein identification by mass spectrometry-based techniques

D. López-Ferrer, B. Cañas, J. Vázquez, C. Lodeiro, R. Rial-Otero, I. Moura, J. L. Capelo

Research output: Contribution to journalArticlepeer-review

56 Citations (Scopus)

Abstract

Rapid identification of proteins is of primary importance for the analytical community. Protein-biomarker discovery for medical diagnostics or pharmacological purposes is becoming one of the hottest research topics. Moreover, rapid identification of proteins can help unambiguous bacterial and virus detection. In addition, the fast identification of bacteria can be used to beat bioterrorism. As a consequence, new analytical methodologies have emerged recently with the aim of making protein analysis as fast and as confident as possible. In this article, we critically review the new trends in sample treatment for protein identification and comment on the prospects for the future in this promising analytical area.

Original languageEnglish
Pages (from-to)996-1005
Number of pages10
JournalTrAC - Trends in Analytical Chemistry
Volume25
Issue number10
DOIs
Publication statusPublished - 1 Nov 2006

Keywords

  • Biomarker
  • Protein
  • Rapid identification
  • Sample treatment

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