Right cardiac intracavitary metastases from a primary intracranial myxofibrosarcoma

Diogo Alpuim Costa, Pedro Barata, Emanuel Gouveia, Manuela Mafra

Research output: Contribution to journalArticlepeer-review


Primary intracranial myxofibrosarcoma is exceedingly rare, with less than 10 cases published. We present a case of a 23-year-old man with previous history of a primary low grade myxofibrosarcoma of the left parietal-occipital convexity resected in March 1999. He subsequently underwent several interventions for multiple local recurrent disease until March 2004. At that time, complete remission was documented. About 8 years later, in February 2012, the patient was admitted to the emergency room with refractory acute pulmonary oedema. On work up, sustained monomorphic ventricular tachycardia and hyperechoic myocardial mass with invasion of the right ventricular cavity were detected. Electrical cardioversion was unsuccessful and irreversible cardiac arrest followed. The autopsy confirmed multiple bilateral lung metastases, malignant pulmonary embolism and myocardial invasion by the primary tumour, with intracavitary cardiac thrombosis and absence of intracranial disease. To the best of our knowledge, this is the first report of extracranial metastases of this neoplasm.

Original languageEnglish
JournalBMJ case reports
Publication statusPublished - 24 Mar 2016


  • Brain Neoplasms
  • Fatal Outcome
  • Fibrosarcoma
  • Heart Neoplasms
  • Humans
  • Lung Neoplasms
  • Male
  • Myxosarcoma
  • Neoplasms, Second Primary
  • Pulmonary Edema
  • Young Adult
  • Case Reports
  • Journal Article


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