Reduction of amides with silanes catalyzed by MoO2Cl2

Ana C. Fernandes, Carlos C. Romão

Research output: Contribution to journalArticlepeer-review

100 Citations (Scopus)


A novel method for the reduction of amides to the corresponding amines using a silane in presence of a catalytic amount of dioxomolybdenum dichloride (10 mol%), in moderate to good yields, is reported. This method is especially suitable for the reduction of tertiary amides with bulky N-substituents.

Original languageEnglish
Pages (from-to)60-63
Number of pages4
JournalJournal of Molecular Catalysis A: Chemical
Issue number1-2
Publication statusPublished - 2 Jul 2007


  • Amides
  • Dioxomolybdenum dichloride
  • Reduction
  • Silanes


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