Recent progress in the field of glycoconjugates

Carina I. C. Crucho, Paula Correia-da-Silva, Krasimira Todorova Markova Petrova, Maria Teresa Barros

Research output: Contribution to journalReview article

19 Citations (Scopus)

Abstract

The ubiquity of glycoconjugates in nature and their role in different biological processes, has led to the development of several methodologies to synthesize these molecules. Synthetic glycoconjugates are now used to answer a variety of glycoconjugate-related biological questions and has provided new potential vaccines against cancer, viral and bacterial infections and new biotechnological tools. This review aim to collect and compile the recent advances in the field of glycopeptides, glycoproteins and glycolipid synthesis and also to update the previous reviews made on this subject. Finally, by highlighting the successes and failures of past research we hope this review will inspire fruitful research in this important medicinal chemistry field.
Original languageEnglish
Pages (from-to)124-132
JournalCarbohydrate Research
Volume402
DOIs
Publication statusPublished - 30 Jan 2015

Keywords

  • Carbohydrates
  • Glycobiology
  • Glycoconjugates

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