Recent Developments in the Biological Activities, Bioproduction, and Applications of Pseudomonas spp. Phenazines

Bruno Serafim; Ana R. Bernardino; Filomena Freitas; Cristiana A. V. Torres

doi:10.3390/molecules28031368

Recent Developments in the Biological Activities, Bioproduction, and Applications of Pseudomonas spp. Phenazines

Bruno Serafim, Ana R. Bernardino, Filomena Freitas, Cristiana A. V. Torres

Research output: Contribution to journal › Review article › peer-review

13 Citations (Scopus)

19 Downloads (Pure)

Abstract

Phenazines are a large group of heterocyclic nitrogen-containing compounds with demonstrated insecticidal, antimicrobial, antiparasitic, and anticancer activities. These natural compounds are synthesized by several microorganisms originating from diverse habitats, including marine and terrestrial sources. The most well-studied producers belong to the Pseudomonas genus, which has been extensively investigated over the years for its ability to synthesize phenazines. This review is focused on the research performed on pseudomonads’ phenazines in recent years. Their biosynthetic pathways, mechanism of regulation, production processes, bioactivities, and applications are revised in this manuscript.

Original language	English
Article number	1368
Number of pages	18
Journal	Molecules
Volume	28
Issue number	3
DOIs	https://doi.org/10.3390/molecules28031368
Publication status	Published - 1 Feb 2023

Keywords

bioprocess
phenazines
Pseudomonasspp

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3390/molecules28031368Licence: CC BY

Recent Developments in the Biological ActivitiesFinal published version, 2.46 MBLicence: CC BY

Cite this

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abstract = "Phenazines are a large group of heterocyclic nitrogen-containing compounds with demonstrated insecticidal, antimicrobial, antiparasitic, and anticancer activities. These natural compounds are synthesized by several microorganisms originating from diverse habitats, including marine and terrestrial sources. The most well-studied producers belong to the Pseudomonas genus, which has been extensively investigated over the years for its ability to synthesize phenazines. This review is focused on the research performed on pseudomonads{\textquoteright} phenazines in recent years. Their biosynthetic pathways, mechanism of regulation, production processes, bioactivities, and applications are revised in this manuscript.",

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AU - Torres, Cristiana A. V.

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N2 - Phenazines are a large group of heterocyclic nitrogen-containing compounds with demonstrated insecticidal, antimicrobial, antiparasitic, and anticancer activities. These natural compounds are synthesized by several microorganisms originating from diverse habitats, including marine and terrestrial sources. The most well-studied producers belong to the Pseudomonas genus, which has been extensively investigated over the years for its ability to synthesize phenazines. This review is focused on the research performed on pseudomonads’ phenazines in recent years. Their biosynthetic pathways, mechanism of regulation, production processes, bioactivities, and applications are revised in this manuscript.

AB - Phenazines are a large group of heterocyclic nitrogen-containing compounds with demonstrated insecticidal, antimicrobial, antiparasitic, and anticancer activities. These natural compounds are synthesized by several microorganisms originating from diverse habitats, including marine and terrestrial sources. The most well-studied producers belong to the Pseudomonas genus, which has been extensively investigated over the years for its ability to synthesize phenazines. This review is focused on the research performed on pseudomonads’ phenazines in recent years. Their biosynthetic pathways, mechanism of regulation, production processes, bioactivities, and applications are revised in this manuscript.

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Recent Developments in the Biological Activities, Bioproduction, and Applications of Pseudomonas spp. Phenazines

Abstract

Keywords

UN SDGs

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