Rapid stoichiometric analysis of G-quadruplexes in solution

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Spectroscopy on a G-string! Currently there is strong interest in the determination of the topology of nucleic acid G-quadruplexes due to their biotechnological potential and biological significance. This requires the evaluation of the strand oligomerization level. Here we demonstrate a method for routine assessment of the stoichiometry of nucleic acid quadruplexes in aqueous solutions.
Original languageUnknown
Pages (from-to)6451-6453
JournalChemistry - A European Journal
Issue number22
Publication statusPublished - 1 Jan 2010

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