Quantitative analysis of endocrine disruptors by comprehensive two-dimensional gas chromatography

Miriany A. Moreira, Leiliane C. Andre, Alexandra Ribeiro, Marco Diogo Richter Gomes da Silva, Zenilda L. Cardeal

Research output: Contribution to journalArticle

4 Citations (Scopus)
6 Downloads (Pure)

Abstract

Comprehensive two-dimensional gas chromatography has been successfully applied to the analysis of various organic contaminants; however, few studies report its use in the analysis of endocrine disrupting compounds. These compounds are suspected to cause dysfunction of the endocrine system in humans and animals. This work describes the development of a method to analyse dibutylphthalate, benzylbutylphthalate, nonylphenol and octylphenol in water using solid-phase microextraction (SPME) and comprehensive two-dimensional gas chromatography with a flame ionisation detector. The merit parameters of the comprehensive two-dimensional gas chromatography with flame ionisation detector method were weighed against a gas chromatography/mass spectrometry-single ion monitoring method of endocrine disrupting compounds analysis. The compounds were evaluated over a concentration range of 0.2 to 6.0 mu g L-1. The use of a two-dimensional chromatography method proved to be advantageous in analysing endocrine disrupting compounds, according to the observed increase of the signal relative to the noise and peak resolution.
Original languageEnglish
Pages (from-to)531-536
JournalJournal Of The Brazilian Chemical Society
Volume26
Issue number3
DOIs
Publication statusPublished - Mar 2015

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Endocrine Disruptors
Gas chromatography
Chemical analysis
Ionization
Detectors
Chromatography
Mass spectrometry
Animals
Impurities
Ions
Water
Monitoring

Keywords

  • Alkylphenols
  • Comprehensive two-dimensional gas chromatography
  • Endocrine disrupting compounds
  • Gas chromatography/mass spectrometry
  • Phthalates

Cite this

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Quantitative analysis of endocrine disruptors by comprehensive two-dimensional gas chromatography. / Moreira, Miriany A.; Andre, Leiliane C.; Ribeiro, Alexandra; Silva, Marco Diogo Richter Gomes da; Cardeal, Zenilda L.

In: Journal Of The Brazilian Chemical Society, Vol. 26, No. 3, 03.2015, p. 531-536.

Research output: Contribution to journalArticle

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AU - Andre, Leiliane C.

AU - Ribeiro, Alexandra

AU - Silva, Marco Diogo Richter Gomes da

AU - Cardeal, Zenilda L.

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