Falencia autonomica pura

Translated title of the contribution: Pure autonomic failure. A case report

J. L. Ducla-Soares, A. Sousa Guerreiro, P. Povoa, E. Alvares, L. Guerreiro, F. Carrilho, M. Santos, J. Figueirinhas, M. Carvalho

Research output: Contribution to journalArticle

2 Citations (Scopus)


We present the case of a 64 year old woman who, in the past 5 years, complained of constipation/diarrhea, hyposudoresis, xerostomy and xerophtalmia, disuria and orthostatic hypotension. Cardiovascular reflexes analysis revealed sympathetic and parasympathetic failure. Norepinephrine was markedly reduced, both lying and after tilt. Norepinephrine infusion determined a significant rise in blood pressure, allowing the diagnosis of denervation hypersensitivity. The diagnosis of Pure Autonomic Failure was made. Therapy with 9 alpha fludrocortisone and metoclopramide was initiated with marked and sustained symptomatic effect.

Original languagePortuguese
Pages (from-to)533-537
Number of pages5
JournalActa medica portuguesa
Issue number11
Publication statusPublished - 1 Dec 1993

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    Ducla-Soares, J. L., Sousa Guerreiro, A., Povoa, P., Alvares, E., Guerreiro, L., Carrilho, F., ... Carvalho, M. (1993). Falencia autonomica pura. Acta medica portuguesa, 6(11), 533-537.