Proteomic analysis of the probiotic Lactobacillus reuteri CRL1098 reveals novel tolerance biomarkers to bile acid-induced stress

Agriculture & Biology

• acid tolerance 7%
• acids 3%
• bacteria 3%
• bile 12%
• bile acids 72%
• biomarkers 58%
• cell growth 9%
• cells 1%
• cholesteremic effect 7%
• choloylglycine hydrolase 9%
• cytosine 6%
• deoxycholic acid 7%
• DNA 2%
• enzymes 7%
• gastrointestinal system 5%
• genes 2%
• growth retardation 4%
• homeostasis 5%
• Lactobacillus 5%
• Lactobacillus reuteri 88%
• ligases 5%
• mass spectrometry 4%
• metabolism 3%
• nucleotides 4%
• physiological response 5%
• probiotics 61%
• proteins 9%
• proteomics 56%
• quantitative polymerase chain reaction 4%
• stress response 4%
• transcription (genetics) 8%
• translation (genetics) 10%
• two-dimensional gel electrophoresis 6%
• vitamin B12 6%

Medicine & Life Sciences

• Bacteria 3%
• Bile 11%
• Bile Acids and Salts 66%
• Biomarkers 41%
• choloylglycine hydrolase 10%
• Cytosine 6%
• Deoxycholic Acid 7%
• DNA Repair 5%
• Electrophoresis, Gel, Two-Dimensional 6%
• Enzymes 9%
• Gastrointestinal Tract 5%
• Genes 2%
• Glycodeoxycholic Acid 10%
• Growth 8%
• Heat-Shock Proteins 6%
• Homeostasis 4%
• Lactobacillus reuteri 100%
• Ligases 6%
• Mass Spectrometry 5%
• Nucleotides 4%
• Probiotics 68%
• Protein Biosynthesis 6%
• Proteins 6%
• Proteomics 59%
• Real-Time Polymerase Chain Reaction 4%
• triphosphoric acid 6%
• Up-Regulation 4%
• Vitamin B 12 6%