Production of poly(vinyl alcohol) (PVA) fibers with encapsulated natural deep eutectic solvent (NADES) using electrospinning

Francisca Mano, Ivo M. Aroso, Susana Barreiros, João Paulo Borges, Rui L. Reis, Ana Rita C Duarte, Alexandre Paiva

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Functionalized electrospun fibers are of great interest for biomedical applications such as in the design of drug delivery systems. Nevertheless, in some cases the molecules of interest have poor solubility in water or have high melting temperatures. These drawbacks can be overcome using deep eutectic solvents. In this work, poly(vinyl alcohol) (PVA), a common biodegradable biopolymer, was used to produce new functionalized fibers with the eutectic mixture choline chloride:citric acid in a molar ratio of (1:1) ChCl:CA (1:1), which was used as a model system. Fibers were produced from an aqueous solution with 7.8% (w/v) and 9.8% (w/v) of 95% hydrolyzed PVA and a 2% (v/v) of ChCl:CA (1:1). Smooth, uniform fibers with an average diameter of 0.4 μm were obtained with a content of 19.8 wt % of ChCl:CA (1:1) encapsulated.

Original languageEnglish
Pages (from-to)2504-2509
Number of pages6
JournalACS SUSTAINABLE CHEMISTRY & ENGINEERING
Volume3
Issue number10
DOIs
Publication statusPublished - Oct 2015

Keywords

  • Electrospinning
  • Natural Deep-eutectic solvents
  • Poly(vinyl alcohol)

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