Chitosan (CS) is a biopolymer with many different applications in the biomedical field because it decreases local inflammation, is biodegradable and hypoallergenic. One of these applications is in bone tissue engineering because it is possible for CS to be used as porous scaffolds and also increases proliferation of osteoblasts . Hydroxyapatite (HA) is the main component of bone and it is widely used in bone regeneration. A CS/HA composite will combine the suitable properties of both materials for hard tissue applications. Due to the piezoelectric character of bone, Yamashita et al. have discovered that electrically polarized HA has an increased biological response . This work attempts to prepare scaffolds of CS and HA nanorods and the new material was tested in vitro for assessing the influence of electrical polarization on osteoblasts growth.
|Place of Publication||Porto, Portugal|
|Publication status||Published - 1 Jan 2015|