Preparation and characterization of zinc and magnesium doped bioglasses

Sílvia Rodrigues Gavinho, Mariana Castro Soares, João Paulo Borges, Jorge Carvalho Silva, Isabel Sá Nogueira, Manuel Pedro Fernandes Graça

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

5 Citations (Scopus)


Peri-implantitis is an infectious disease that affects about one of five patients who receive a dental implant within 5 years after the surgery. To minimize this reaction the development of new biomaterials with antibacterial action is needed that can be used as a coating material in orthodontic implants. In addition, these biomaterials can be doped with several ions, which add specific properties that may act at the cellular level, such as increasing the angiogenesis efficiency. In this work, 45S5 Bioglass® has been used as the base material because it presents higher bioactivity compared to other biomaterials. To add antibacterial function and increase positive effects on bone metabolism, zinc and magnesium ions were introduced in the glass network. The main objective was the synthesis of the 45S5 glass by melt-quenching and study the biological performance as function of the zinc and magnesium concentrations. The structural and biological properties of the prepared samples are discussed.

Original languageEnglish
Title of host publicationNATO Science for Peace and Security Series B: Physics and Biophysics
EditorsP. Petkov, M. Achour, C. Popov
Place of PublicationDordrecht
Number of pages11
ISBN (Electronic)978-94-024-2018-0
ISBN (Print)978-94-024-2044-9
Publication statusPublished - 2020

Publication series

NameNATO Science for Peace and Security Series B: Physics and Biophysics
ISSN (Print)1874-6500
ISSN (Electronic)1874-6535


  • Antibacterial properties
  • Bioactive glass
  • Biomaterial
  • Cytotoxicity
  • Implant coating


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