@article{a3aaaaf8778743e18cf94d87e6199ed6,
title = "Preliminary structural characterization of human SOUL, a haem-binding protein",
abstract = "Human SOUL (hSOUL) is a 23 kDa haem-binding protein that was first identified as the PP23 protein isolated from human full-term placentas. Here, the overexpression, purification and crystallization of hSOUL are reported. The crystals belonged to space group P6422, with unit-cell parameters a = b = 145, c = 60 {\AA} and one protein molecule in the asymmetric unit. X-ray diffraction data were collected to 3.5 {\AA} resolution at the ESRF. A preliminary model of the three-dimensional structure of hSOUL was obtained by molecular replacement using the structures of murine p22HBP (PDB codes 2gov and 2hva), obtained by solution NMR, as search models.",
keywords = "Haem-binding proteins, SOUL",
author = "Filipe Freire and Rom{\~a}o, {Maria Jo{\~a}o} and MacEdo, {Anjos L.} and Aveiro, {Susana S.} and Goodfellow, {Brian J.} and Carvalho, {Ana Lu{\'i}sa}",
note = "info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBD%2F30239%2F2006/PT# info:eu-repo/grantAgreement/FCT/5876-PPCDTI/64203/PT# info:eu-repo/grantAgreement/FCT/Concurso para Projectos de I&D em todos os Dom{\'i}nios Cient{\'i}ficos - 2006/PTDC%2FQUI%2F64203%2F2006/PT# The authors acknowledge financial support from Fundacao para a Ciencia e Tecnologia, Portugal through grant SFRH/BPD/30239/2006. The authors also acknowledge the ESRF, Grenoble (beamlines ID14- EH2, ID14- EH4, ID23- EH1 and ID-29) for access and technical support during data collection.",
year = "2009",
month = jan,
day = "1",
doi = "10.1107/S174430910902291X",
language = "English",
volume = "65",
pages = "723--726",
journal = "Acta Crystallographica Section F: Structural Biology and Crystallization Communications",
issn = "1744-3091",
publisher = "Blackwell Publishing Ltd",
number = "7",
}