Positive and negative ion formation via slow electron collisions with 5-bromouridine

Stephan Denifl, Pietro Candori, Sylwia Ptasinska, Paulo Manuel Assis Loureiro Limão-vieira, Verena Grill, T. D. Märk, P. Scheier

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

Cation and anion formation is studied experimentally upon inelastic low energy electron interactions with 5-bromouridine (BrUrd) using a crossed electron/neutral beams set-up combined with a quadrupole mass spectrometer. The BrUrd molecule belongs to the class of radiosensitizers that increase the sensitivity of DNA (or RNA) to ionizing radiation. In the case of positive ion formation the ionization efficiency curves are measured near the threshold and the corresponding appearance energies are determined using a non-linear least square fitting procedure. The anion yields are investigated in the electron energy range from about 0 to 14 eV. From the comparison of the present results for negative and positive ions information concerning the underlying mechanism of radiosensitizers is deduced.
Original languageEnglish
Pages (from-to)391-398
Number of pages8
JournalEuropean Physical Journal D
Volume35
Issue number2
DOIs
Publication statusPublished - Aug 2005

Keywords

  • Anion Yield
  • Anion Formation
  • Quadrupole Mass Spectrometer
  • Electron Interaction
  • Ionization Efficiency

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